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Query author contributions in Reactome

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Details on Person SETD8 [nucleoplasm]

Class:IdEntityWithAccessionedSequence:417142
_displayNameSETD8 [nucleoplasm]
_timestamp2015-03-04 05:56:51
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:417139] May, B, 2009-04-11 07:43:47
endCoordinate393
modified[InstanceEdit:417164] May, B, 2009-04-11 07:48:22
[InstanceEdit:2301200] Orlic-Milacic, M, 2012-06-04
[InstanceEdit:3239028] Jupe, S, 2013-03-27
[InstanceEdit:5651644] Jupe, Steve, 2014-11-24
nameSETD8
Histone-lysine N-methyltransferase SETD8
SETD8_HUMAN
KMT5A
SET8
referenceEntity[ReferenceGeneProduct:64346] UniProt:Q9NQR1 KMT5A [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:5648312] R-HSA-417142.1
startCoordinate1
(activeUnit)[NegativeGeneExpressionRegulation:9815610] Negative gene expression regulation by 'ZEB1:CDH1 gene, SMARCA4:ZEB1:CDH1 gene, HDAC1,(HDAC2):TLE1:ZEB1:CDH1 gene, (SETD8:ZEB1:CDH1 gene, SIRT1:MPHOSPH8:ZEB1:CDH1 gene) [nucleoplasm]'
[NegativeGeneExpressionRegulation:9815628] Negative gene expression regulation by 'TWIST1:CDH1 gene, (SETD8:TWIST1:CDH1 gene) [nucleoplasm]'
(hasComponent)[Complex:212146] General Chromatin Replication Complex [nucleoplasm] [Homo sapiens]
[Complex:9931110] SET8:TWIST1:CDH1 gene [nucleoplasm] [Homo sapiens]
[Complex:9931117] SETD8:ZEB1:CDH1 gene [nucleoplasm] [Homo sapiens]
(hasMember)[CandidateSet:1183246] Histone-lysine methyltransferases [nucleoplasm] [Homo sapiens]
(input)[Reaction:9765788] TWIST1 recruits SETD8 to CDH1 gene promoter [Homo sapiens]
[Reaction:9765791] ZEB1 recruits SETD8 to CDH1 gene promoter [Homo sapiens]
(physicalEntity)[CatalystActivity:2301204] histone H4K20 methyltransferase activity of SETD8 [nucleoplasm]
[CatalystActivity:5651645] histone H4 methyltransferase activity of SETD8 [nucleoplasm]
[CatalystActivity:6805744] lysine N-methyltransferase activity of SETD8 [nucleoplasm]
(updatedInstance)[_UpdateTracker:9891646] Update Tracker - [EntityWithAccessionedSequence:417142] SETD8 [nucleoplasm] - v52:[addName]
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No pathways have been reviewed or authored by SETD8 [nucleoplasm] (417142)