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Details on Person Sema4D-mediated attraction of endothelial cells requires Rho...
| Class:Id | Summation:416602 |
|---|---|
| _displayName | Sema4D-mediated attraction of endothelial cells requires Rho... |
| _timestamp | 2009-03-30 15:33:21 |
| created | [InstanceEdit:416590] Garapati, P V, 2009-03-30 15:26:31 |
| literatureReference | [LiteratureReference:399751] Semaphorin signaling: progress made and promises ahead |
| modified | [InstanceEdit:416605] Garapati, P V, 2009-03-30 15:33:04 |
| text | Sema4D-mediated attraction of endothelial cells requires Rho, but not R-Ras, signaling. Sema4D-mediated plexinB1 activation activates Rho and its downstream effector ROCK. ROCK then phosphorylates MLC to induce actomyosin stress fiber contraction and to direct the assembly of focal adhesion complexes and integrin-mediated adhesion. |
| (summation) | [Pathway:416572] Sema4D induced cell migration and growth-cone collapse [Homo sapiens] |
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No pathways have been reviewed or authored by Sema4D-mediated attraction of endothelial cells requires Rho... (416602)
