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Details on Person UniProt:Q9NR81 ARHGEF3
| Class:Id | ReferenceGeneProduct:414718 |
|---|---|
| _chainChangeLog | chain:1-526 added on Fri February 6 2015 |
| _displayName | UniProt:Q9NR81 ARHGEF3 |
| _timestamp | 2024-11-03 19:49:57 |
| chain | chain:1-526 |
| checksum | 0FE8248AB52D1CBC |
| comment | FUNCTION Acts as a guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.SUBUNIT Interacts with RHOA and RHOB.INTERACTION Widely expressed. Highest levels are found in adult brain and skeletal muscle. Lower levels are found in heart and kidney. |
| created | [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 |
| description | recommendedName: Rho guanine nucleotide exchange factor 3 alternativeName: Exchange factor found in platelets and leukemic and neuronal tissues shortName: XPLN |
| geneName | ARHGEF3 |
| identifier | Q9NR81 |
| isSequenceChanged | FALSE |
| keyword | Alternative splicing Cytoplasm Guanine-nucleotide releasing factor Phosphoprotein Proteomics identification Reference proteome |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9862192] Weiser, Joel, 2024-02-26 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | ARHGEF3 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8962243] ENSEMBL:ENSG00000163947 ARHGEF3 [Homo sapiens] |
| secondaryIdentifier | ARHG3_HUMAN A8K5U7 Q4FZB6 Q4QQI5 Q4QQQ0 Q59F00 Q6NUN3 Q7Z4U2 Q7Z5T2 Q9H7T4 |
| sequenceLength | 526 |
| species | [Species:48887] Homo sapiens |
| (isoformParent) | [ReferenceIsoform:194993] UniProt:Q9NR81-2 ARHGEF3 [Homo sapiens] [ReferenceIsoform:194996] UniProt:Q9NR81-1 ARHGEF3 [Homo sapiens] [ReferenceIsoform:219028] UniProt:Q9NR81-3 ARHGEF3 [Homo sapiens] [ReferenceIsoform:219029] UniProt:Q9NR81-4 ARHGEF3 [Homo sapiens] |
| (referenceEntity) | [EntityWithAccessionedSequence:2976629] ARHGEF3 [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9NR81 ARHGEF3 (414718)
