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Details on Person UniProt:Q8BH15-1 Cnot10
| Class:Id | ReferenceIsoform:410075 |
|---|---|
| _chainChangeLog | initiator methionine:1 added on Fri February 6 2015;chain:2-744 added on Fri February 6 2015;initiator methionine:1 for 410075 removed on Fri Nov 03 2023;initiator methionine: for 410075 added on Fri Nov 03 2023;initiator methionine: for 410075 removed on Fri Aug 15 2025;initiator methionine:1 for 410075 added on Fri Aug 15 2025 |
| _displayName | UniProt:Q8BH15-1 Cnot10 |
| _timestamp | 2025-08-15 22:07:01 |
| chain | initiator methionine:1 chain:2-744 |
| checksum | 598C842BD70BC819 |
| comment | FUNCTION Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex (By similarity).SUBUNIT Component of the CCR4-NOT complex; distinct complexes seem to exist that differ in the participation of probably mutually exclusive catalytic subunits. CNOT10 and CNOT11 form a subcomplex docked to the CNOT1 scaffold (By similarity).SUBCELLULAR LOCATION Belongs to the CNOT10 family. |
| created | [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 |
| description | recommendedName: CCR4-NOT transcription complex subunit 10 |
| geneName | Cnot10 |
| identifier | Q8BH15 |
| isoformParent | |
| isSequenceChanged | FALSE |
| keyword | Acetylation Alternative splicing Coiled coil Cytoplasm Nucleus Reference proteome RNA-mediated gene silencing Transcription Transcription regulation Translation regulation |
| modified | [InstanceEdit:423310] Kanapin, AA [InstanceEdit:435478] Kanapin, AA [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:3445779] Weiser, JD [InstanceEdit:4341137] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9657908] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | Cnot10 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | CNO10_MOUSE Q05CH8 Q3TSS4 Q3UDS5 Q80VN2 Q8CI74 |
| sequenceLength | 744 |
| species | [Species:48892] Mus musculus |
| variantIdentifier | Q8BH15-1 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q8BH15-1 Cnot10 (410075)
