Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person p-TIAM1 exchanges GTP for GDP on RAC1, activating it

Class:Id	Reaction:4093336
_displayName	p-TIAM1 exchanges GTP for GDP on RAC1, activating it
_doRelease	TRUE
_timestamp	2014-11-20 02:48:02
authored	[InstanceEdit:3928653] Garapati, P V, 2013-07-22
catalystActivity	[CatalystActivity:4093333] guanyl-nucleotide exchange factor activity of EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:p-Y829-TIAM1 [plasma membrane]
catalystActivityReference	[CatalystActivityReference:9643889] guanyl-nucleotide exchange factor activity of EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:p-Y829-TIAM1 [plasma membrane] The Rac1-GEF Tiam1 couples the NMDA receptor to the activity-dependent development of dendritic arbors and spines
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:4093334] Garapati, P V, 2013-08-14
edited	[InstanceEdit:3928653] Garapati, P V, 2013-07-22
input	[SimpleEntity:29438] GTP [cytosol] [Complex:445010] RAC1:GDP [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:4093277] The Rac1-GEF Tiam1 couples the NMDA receptor to the activity-dependent development of dendritic arbors and spines
modified	[InstanceEdit:4443762] Garapati, P V, 2013-09-03 [InstanceEdit:4640897] Garapati, P V, 2013-09-27 [InstanceEdit:5096527] Garapati, P V, 2013-11-11 [InstanceEdit:5096559] Garapati, P V, 2013-11-11 [InstanceEdit:5097236] Garapati, P V, 2013-11-11 [InstanceEdit:5099816] Garapati, P V, 2013-11-12 [InstanceEdit:5144541] Garapati, P V, 2013-11-18 [InstanceEdit:5490336] Garapati, P V, 2014-05-19 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	p-TIAM1 exchanges GTP for GDP on RAC1, activating it
output	[SimpleEntity:29420] GDP [cytosol] [Complex:442641] RAC1:GTP [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:3928627] EPHB phosphorylates TIAM1 [Homo sapiens] [Reaction:3928645] EPHB:NMDAR binds TIAM1 [Homo sapiens]
releaseDate	2014-06-10
reviewed	[InstanceEdit:5490284] Ip, Nancy Y, 2014-05-19
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5644839] R-HSA-4093336.3
summation	[Summation:4093260] Phosphorylated T-lymphoma invasion and metastasis-inducing p...
(hasEvent)	[Pathway:3928662] EPHB-mediated forward signaling [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by p-TIAM1 exchanges GTP for GDP on RAC1, activating it (4093336)