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Details on Person SUMOylation of ELK1 with SUMO2,3

Class:Id	Reaction:4090336
_displayName	SUMOylation of ELK1 with SUMO2,3
_timestamp	2022-01-18 18:47:28
authored	[InstanceEdit:4086098] May, B, 2013-08-06
catalystActivity	[CatalystActivity:3246099] SUMO transferase activity of UBE2I:SUMO2,UBE2I:SUMO3 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:4090291] May, B, 2013-08-13
edited	[InstanceEdit:4086098] May, B, 2013-08-06
input	[EntityWithAccessionedSequence:3009346] ELK1 [nucleoplasm] [Homo sapiens] [DefinedSet:3899312] UBE2I:SUMO2,UBE2I:SUMO3 [nucleoplasm] [Homo sapiens] [DefinedSet:3899312] UBE2I:SUMO2,UBE2I:SUMO3 [nucleoplasm] [Homo sapiens] [DefinedSet:3899312] UBE2I:SUMO2,UBE2I:SUMO3 [nucleoplasm] [Homo sapiens] [DefinedSet:3899312] UBE2I:SUMO2,UBE2I:SUMO3 [nucleoplasm] [Homo sapiens] [DefinedSet:3899312] UBE2I:SUMO2,UBE2I:SUMO3 [nucleoplasm] [Homo sapiens] [DefinedSet:3899312] UBE2I:SUMO2,UBE2I:SUMO3 [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:4090415] Dynamic interplay of the SUMO and ERK pathways in regulating Elk-1 transcriptional activity [LiteratureReference:4090395] SUMOylation regulates nucleo-cytoplasmic shuttling of Elk-1
modified	[InstanceEdit:4663810] May, B, 2013-10-06 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9762188] May, Bruce, 2022-01-18
name	SUMOylation of ELK1 with SUMO2,3
output	[EntityWithAccessionedSequence:4090425] polySUMO2,3-K230,K249,K254-ELK1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912481] UBE2I [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912481] UBE2I [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912481] UBE2I [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912481] UBE2I [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912481] UBE2I [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:912481] UBE2I [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:2993790] Transfer of SUMO2 from E1 to UBE2I (UBC9) [Homo sapiens] [Reaction:2993784] Conjugation of SUMO2 to UBA2:SAE1 [Homo sapiens] [Reaction:2993769] Transfer of SUMO3 from E1 to UBE2I (UBC9) [Homo sapiens] [Reaction:2993781] Conjugation of SUMO3 to UBA2:SAE1 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8886887] R-HSA-4090336.1
summation	[Summation:4090400] ELK1 is SUMOylated at lysine-230, lysine-249, and lysine-254...
(hasEvent)	[Pathway:3232118] SUMOylation of transcription factors [Homo sapiens]
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