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Details on Person Endostatin binds to the integrins alphaVbeta3, alphaVbeta5, ...
| Class:Id | Summation:4088263 |
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| _displayName | Endostatin binds to the integrins alphaVbeta3, alphaVbeta5, ... |
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| _timestamp | 2013-08-12 13:42:34 |
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| created | [InstanceEdit:4088261] Jupe, S, 2013-08-12 |
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| literatureReference | [LiteratureReference:4088230] Interaction of endostatin with integrins implicated in angiogenesis
[LiteratureReference:4088256] Molecular interplay between endostatin, integrins, and heparan sulfate
[LiteratureReference:4088274] Target-derived matricryptins organize cerebellar synapse formation through ?3?1 integrins
[LiteratureReference:4088224] Unraveling the mysteries of endostatin |
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| text | Endostatin binds to the integrins alphaVbeta3, alphaVbeta5, alpha5beta1 (Rehn et al. 2001, Faye et al. 2009) and alpha3beta1 (Su et al. 2012). Endostatin is the cleaved non-collagenous C ternminal domain of collagen alpha-1(XVIII) a member of the multiplexin family. It inhibits endothelial cell migration, proliferation, and angiogenesis (Fu et al. 2009). |
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| (summation) | [Reaction:4088264] Endostatin binds integrin alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 [Homo sapiens] |
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