Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate

Class:Id	Reaction:4085217
_displayName	NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate
_doRelease	TRUE
_timestamp	2023-08-14 20:55:16
authored	[InstanceEdit:4085207] Jassal, Bijay, 2013-08-02
catalystActivity	[CatalystActivity:4088105] N-acetylneuraminate lyase activity of NPL tetramer [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:4085207] Jassal, Bijay, 2013-08-02
edited	[InstanceEdit:4085207] Jassal, Bijay, 2013-08-02
input	[DefinedSet:4088096] Neu5Ac, Neu5Gc [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:4088182] A novel splice variant of human gene NPL, mainly expressed in human liver, kidney and peripheral blood leukocyte [LiteratureReference:4088177] Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N-glycolylneuraminic acid
modified	[InstanceEdit:4088093] Jassal, Bijay, 2013-08-09 [InstanceEdit:4088171] Jassal, B, 2013-08-12 [InstanceEdit:4612646] Jassal, Bijay, 2013-09-26 [InstanceEdit:5096550] Jassal, Bijay, 2013-11-11 [InstanceEdit:5144547] Jassal, Bijay, 2013-11-18 [InstanceEdit:5225589] Jassal, Bijay, 2014-01-08 [InstanceEdit:5251381] Jassal, Bijay, 2014-02-03 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9841807] Matthews, Lisa, 2023-08-14
name	NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate
output	[DefinedSet:4088099] ManNAc,ManNGc [cytosol] [SimpleEntity:29398] PYR [cytosol]
precedingEvent	[Reaction:428585] SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol [Homo sapiens] [Reaction:4084999] NEU1 hydrolyses Neu5Ac from glycoconjugates [Homo sapiens] [Reaction:4085029] NEU2 hydrolyzes Neu5Ac from glycoconjugates [Homo sapiens] [BlackBoxEvent:4088205] Plasma membrane glycoconjugates translocate to the cytosol [Homo sapiens] [Reaction:4084994] NEU3 hydrolyzes Neu5Ac from glycoconjugates [Homo sapiens] [BlackBoxEvent:4088207] Golgi lumen glycoconjugates translocate to the plasma membrane [Homo sapiens]
releaseDate	2014-03-12
reviewed	[InstanceEdit:5225590] Medrano, Juan F, Wickramasinghe, Saumya, 2014-01-08
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5644918] R-HSA-4085217.3
summation	[Summation:4088180] Once in the cytosol, sialic acids are either reutilized or d...
(hasEvent)	[Pathway:4085001] Sialic acid metabolism [Homo sapiens]
(precedingEvent)	[Reaction:6803761] RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (4085217)