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Details on Person ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link)
Class:Id Reaction:4085033
_displayName ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link)
_doRelease TRUE
_timestamp 2023-08-14 20:55:30
authored [InstanceEdit:4085031] Jassal, Bijay, 2013-08-01
catalystActivity [CatalystActivity:4086276] beta-galactoside alpha-2,6-sialyltransferase activity of ST6GAL1,2 [Golgi membrane]
compartment [Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created [InstanceEdit:4085031] Jassal, Bijay, 2013-08-01
edited [InstanceEdit:4085031] Jassal, Bijay, 2013-08-01
input [SimpleEntity:4086285] Gal-R [Golgi lumen] [SimpleEntity:727815] CMP-Neu5Ac [Golgi lumen]
isChimeric FALSE
literatureReference [LiteratureReference:4086247] Universal phosphatase-coupled glycosyltransferase assay [LiteratureReference:4086342] Characterization of the second type of human beta-galactoside alpha 2,6-sialyltransferase (ST6Gal II), which sialylates Galbeta 1,4GlcNAc structures on oligosaccharides preferentially. Genomic analysis of human sialyltransferase genes [LiteratureReference:1015848] Identification and functional expression of a second human beta-galactoside alpha2,6-sialyltransferase, ST6Gal II
modified [InstanceEdit:4086245] Jassal, Bijay, 2013-08-07 [InstanceEdit:4088183] Jassal, Bijay, 2013-08-12 [InstanceEdit:4088189] Jassal, Bijay, 2013-08-12 [InstanceEdit:4612646] Jassal, Bijay, 2013-09-26 [InstanceEdit:5096550] Jassal, Bijay, 2013-11-11 [InstanceEdit:5144547] Jassal, Bijay, 2013-11-18 [InstanceEdit:5225589] Jassal, Bijay, 2014-01-08 [InstanceEdit:5251381] Jassal, Bijay, 2014-02-03 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9841785] Stephan, Ralf, 2023-08-12 [InstanceEdit:9841807] Matthews, Lisa, 2023-08-14
name ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link)
output [SimpleEntity:727810] CMP [Golgi lumen] [SimpleEntity:4086294] Neu5Ac-2,6-Gal-R [Golgi lumen]
precedingEvent
releaseDate 2014-03-12
reviewed [InstanceEdit:5225590] Medrano, Juan F, Wickramasinghe, Saumya, 2014-01-08
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:5644328] R-HSA-4085033.3
summation [Summation:4086306] The beta-galactoside alpha-2,6-sialyltransferases 1 and 2 (S...
(hasEvent) [Pathway:4085001] Sialic acid metabolism [Homo sapiens]
(precedingEvent) [BlackBoxEvent:4088207] Golgi lumen glycoconjugates translocate to the plasma membrane [Homo sapiens]
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