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Details on Person UniProt:Q15723-1 ELF2
| Class:Id | ReferenceIsoform:405883 |
|---|---|
| _chainChangeLog | chain:1-593 added on Fri February 6 2015 |
| _displayName | UniProt:Q15723-1 ELF2 |
| _timestamp | 2024-11-03 19:56:04 |
| chain | chain:1-593 |
| checksum | B67013B453559910 |
| comment | FUNCTION Isoform 1 transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter.FUNCTION Isoform 2 may function in repression of RUNX1-mediated transactivation.SUBUNIT Interacts with the LIM domains of LMO2 (By similarity). Interacts via its N-terminal region with RUNX1.INTERACTION Expressed in all fetal and adult tissues examined. Among fetal tissues, highest levels of expression detected in heart, lung, liver and kidney, and lower levels in brain. Among adult tissues, highest levels of expression detected in heart, placenta, lung, skeletal muscle, spleen, thymus, testis and ovary. Moderate expression in prostate, small intestine, kidney, liver and pancreas, and weak expression in colon, brain and peripheral blood lymphocytes.SIMILARITY Belongs to the ETS family. |
| created | [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 |
| description | recommendedName: ETS-related transcription factor Elf-2 alternativeName: E74-like factor 2 alternativeName: New ETS-related factor |
| geneName | ELF2 NERF |
| identifier | Q15723 |
| isoformParent | |
| isSequenceChanged | FALSE |
| keyword | Activator Alternative splicing DNA-binding Isopeptide bond Methylation Nucleus Phosphoprotein Proteomics identification Reference proteome Transcription Transcription regulation Ubl conjugation |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | ELF2 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8994199] ENSEMBL:ENSG00000109381 ELF2 [Homo sapiens] |
| secondaryIdentifier | ELF2_HUMAN E9PCX3 Q15724 Q15725 Q6P1K5 |
| sequenceLength | 593 |
| species | [Species:48887] Homo sapiens |
| variantIdentifier | Q15723-1 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q15723-1 ELF2 (405883)
