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Details on Person G alpha (q) binds to Trio family RhoGEFs

Class:Id	Reaction:400586
_displayName	G alpha (q) binds to Trio family RhoGEFs
_doRelease	TRUE
_timestamp	2017-07-11 09:37:18
authored	[InstanceEdit:400704] Jupe, S, 2009-03-24 18:05:59
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:400585] Jupe, S, 2009-03-24 10:19:21
edited	[InstanceEdit:435382] Jupe, S, 2009-09-09
input	[DefinedSet:399963] TRIO family RhoGEFs [cytosol] [Homo sapiens] [Complex:114534] G-protein alpha (q/11): GTP [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:400587] Assembly of high order G alpha q-effector complexes with RGS proteins
modified	[InstanceEdit:400700] Jupe, S, 2009-03-24 18:00:22 [InstanceEdit:416347] Jupe, S, 2009-03-26 09:39:59 [InstanceEdit:416470] Jupe, S, 2009-03-27 12:34:19 [InstanceEdit:420853] Jassal, Bijay, 2009-05-14 [InstanceEdit:425218] Jupe, S, 2009-06-03 [InstanceEdit:427697] Jupe, S, 2009-06-23 [InstanceEdit:428751] Jupe, S, 2009-07-09 [InstanceEdit:430261] Jupe, S, 2009-08-06 [InstanceEdit:435182] Jupe, S, 2009-09-07 [InstanceEdit:435383] Jupe, S, 2009-09-09 [InstanceEdit:508592] Jupe, S, 2010-02-15 [InstanceEdit:749449] Jupe, S, 2010-05-18 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8983501] Varusai, Thawfeek, 2017-03-24 [InstanceEdit:9012089] Varusai, Thawfeek, 2017-07-11 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	G alpha (q) binds to Trio family RhoGEFs
output	[Complex:400608] G-protein alpha (q/11):Trio family RhoGEFs [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:418576] Dissociation of the P2Y purinoceptor 1:Gq complex [Homo sapiens] [Reaction:418579] Gq activation by P2Y purinoceptor 1 [Homo sapiens] [Reaction:397835] Thrombin-activated PARs:Gq (active) dissociate [Homo sapiens] [Reaction:114558] Thrombin-activated PARs activate Gq [Homo sapiens] [Reaction:428752] Dissociation of the TP:Gq complex [Homo sapiens] [Reaction:428750] Gq activation by TP receptor [Homo sapiens] [Reaction:749452] The Ligand:GPCR:Gq complex dissociates [Homo sapiens] [Reaction:379048] Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 [Homo sapiens]
releaseDate	2009-09-30
reviewed	[InstanceEdit:425201] Akkerman, JW, 2009-06-03
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:9012014] Varusai, Thawfeek, 2017-07-10
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104393] R-HSA-400586.4
summation	[Summation:400701] The Trio family of RhoA guanine nucleotide exchange factors ...
(hasEvent)	[Pathway:416476] G alpha (q) signalling events [Homo sapiens]
(precedingEvent)	[Reaction:376148] Trio family RhoGEFs activate RhoA [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9790780] Update Tracker - [Reaction:400586] G alpha (q) binds to Trio family RhoGEFs - v33:[add_removeInput] [_UpdateTracker:9791186] Update Tracker - [Reaction:400586] G alpha (q) binds to Trio family RhoGEFs - v32:[add_removeInput]
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