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Details on Person Signal peptidase hydrolyzes preproGIP to proGIP

Class:Id	Reaction:400496
_displayName	Signal peptidase hydrolyzes preproGIP to proGIP
_doRelease	TRUE
_timestamp	2014-02-04 22:52:48
authored	[InstanceEdit:421433] May, B, 2009-05-18 21:31:59
catalystActivity	[CatalystActivity:265014] serine-type endopeptidase activity of Signal Peptidase [endoplasmic reticulum membrane]
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:400497] May, B, 2009-03-24 03:41:55
edited	[InstanceEdit:435259] May, B, 2009-09-09
inferredFrom	[Reaction:445309] Signal Peptidase (Canis) hydrolyzes the signal peptide of Preprolactin [Bos taurus]
input	[EntityWithAccessionedSequence:400470] GIP(1-153) [endoplasmic reticulum lumen] [Homo sapiens]
literatureReference	[LiteratureReference:508203] Sequence of an intestinal cDNA encoding human gastric inhibitory polypeptide precursor
modified	[InstanceEdit:422152] D'Eustachio, P, 2009-05-26 22:15:13 [InstanceEdit:422548] D'Eustachio, P, 2009-06-02 00:49:41 [InstanceEdit:434234] May, B, 2009-08-27 [InstanceEdit:435259] May, B, 2009-09-09 [InstanceEdit:435295] May, B, 2009-09-09 [InstanceEdit:508224] May, B, 2010-02-11 [InstanceEdit:771698] May, B, 2010-05-21 [InstanceEdit:847708] May, B, 2010-05-30 [InstanceEdit:879885] May, B, 2010-06-24 [InstanceEdit:927719] May, B, 2010-08-06 [InstanceEdit:5251722] May, B, 2014-02-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Signal peptidase hydrolyzes preproGIP to proGIP
output	[EntityWithAccessionedSequence:400512] GIP(22-153) [endoplasmic reticulum lumen] [Homo sapiens]
precedingEvent	[BlackBoxEvent:400500] Synthesis of prepro-Glucose-dependent Insulinotropic Polypeptide (preproGIP) in intestinal K cells [Homo sapiens]
releaseDate	2010-09-21
reviewed	[InstanceEdit:879883] Bloom, SR, 2010-06-24
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104211] R-HSA-400496.2
summation	[Summation:400561] The GIP mRNA is translated by ribosomes at the outer surface...
(hasEvent)	[Pathway:400511] Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:421426] ProGIP translocates from the ER Lumen to secretory granules [Homo sapiens]
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No pathways have been reviewed or authored by Signal peptidase hydrolyzes preproGIP to proGIP (400496)