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Details on Person PCSK1 hydrolyzes proGIP to GIP

Class:IdReaction:400492
_displayNamePCSK1 hydrolyzes proGIP to GIP
_doReleaseTRUE
_timestamp2014-02-04 22:51:47
authored[InstanceEdit:421433] May, B, 2009-05-18 21:31:59
catalystActivity[CatalystActivity:378987] serine-type endopeptidase activity of PC1:calcium cofactor [secretory granule lumen]
compartment[Compartment:1462052] secretory granule lumen
created[InstanceEdit:400497] May, B, 2009-03-24 03:41:55
edited[InstanceEdit:435259] May, B, 2009-09-09
inferredFrom
input[EntityWithAccessionedSequence:400526] GIP(22-153) [secretory granule lumen] [Homo sapiens]
modified[InstanceEdit:421425] May, B, 2009-05-18 21:31:00
[InstanceEdit:422152] D'Eustachio, P, 2009-05-26 22:15:13
[InstanceEdit:422548] D'Eustachio, P, 2009-06-02 00:49:41
[InstanceEdit:434236] May, B, 2009-08-27
[InstanceEdit:435259] May, B, 2009-09-09
[InstanceEdit:435295] May, B, 2009-09-09
[InstanceEdit:508224] May, B, 2010-02-11
[InstanceEdit:771698] May, B, 2010-05-21
[InstanceEdit:847708] May, B, 2010-05-30
[InstanceEdit:879885] May, B, 2010-06-24
[InstanceEdit:927719] May, B, 2010-08-06
[InstanceEdit:2684523] D'Eustachio, P, 2012-11-30
[InstanceEdit:2980769] May, B, 2013-01-11
[InstanceEdit:5251722] May, B, 2014-02-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePCSK1 hydrolyzes proGIP to GIP
output[EntityWithAccessionedSequence:400483] GIP(52-93) [secretory granule lumen] [Homo sapiens]
precedingEvent
releaseDate2010-09-21
reviewed[InstanceEdit:879883] Bloom, SR, 2010-06-24
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1104137] R-HSA-400492.2
summation[Summation:400489] Prohormone Convertase 1/3 in secretory granules cleaves Gluc...
(hasEvent)[Pathway:400511] Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) [Homo sapiens]
(precedingEvent)[BlackBoxEvent:400509] Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells [Homo sapiens]
(updatedInstance)[_UpdateTracker:9787914] Update Tracker - [Reaction:400492] PCSK1 hydrolyzes proGIP to GIP - v44:[add_removeCatalystActivity]
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