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Details on Person SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins

Class:IdLiteratureReference:400236
_displayNameSCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins
_timestamp2018-07-11 13:41:51
author[Person:400395] Busino, L
[Person:400254] Bassermann, F
[Person:400296] Maiolica, A
[Person:200246] Lee, C
[Person:400372] Nolan, PM
[Person:400321] Godinho, SI
[Person:187518] Draetta, GF
[Person:174134] Pagano, Michele
created[InstanceEdit:400303] May, B, 2009-03-24 02:57:07
journalScience
modified[InstanceEdit:9613060] D'Eustachio, Peter, 2018-07-11
pages900-4
pubMedIdentifier17463251
titleSCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins
volume316
year2007
(literatureReference)[Pathway:9909396] Circadian clock [Homo sapiens]
[Pathway:9932298] Degradation of CRY and PER proteins [Homo sapiens]
[BlackBoxEvent:9932501] Fbxl3:Cul1:Skp1:Rbx1 ubiquitinylates phosphorylated Cry1,2 [Mus musculus]
[Reaction:9932519] Fbxl3:Cul1:Skp1:Rbx1 binds phosphorylated Cry1,2 [Mus musculus]
[BlackBoxEvent:9934892] Proteolysis of K48polyUb,p-S-Cry1,2 [Mus musculus]
[Complex:508657] Fbxl3:p-Cry [nucleoplasm] [Mus musculus]
[DefinedSet:517938] K48polyUb-K,p-S-CRY1,2 [nucleoplasm] [Homo sapiens]
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