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Details on Person SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein
| Class:Id | LiteratureReference:400234 |
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| _displayName | SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein |
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| _timestamp | 2009-03-24 03:05:43 |
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| author | [Person:400248] Shirogane, T
[Person:114007] Jin, J
[Person:400288] Ang, XL
[Person:188354] Harper, JW |
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| created | [InstanceEdit:400303] May, B, 2009-03-24 02:57:07 |
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| journal | J Biol Chem |
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| pages | 26863-72 |
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| pubMedIdentifier | 15917222 |
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| title | SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein |
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| volume | 280 |
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| year | 2005 |
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| (literatureReference) | [Complex:400368] Beta-TrCP1:PER [cytosol] [Homo sapiens]
[Complex:508758] Beta-TrCP (Btrc):p-Per [cytosol] [Mus musculus]
[Summation:9930072] In the cytosol the kinases casein kinase I delta (CSNK1D) an...
[Pathway:9909396] Circadian clock [Homo sapiens]
[Pathway:9932298] Degradation of CRY and PER proteins [Homo sapiens]
[BlackBoxEvent:9932505] Btrc:Cul1:Skp1:Rbx1 ubiquitinylates phosphorylated Per1,2,3 [Mus musculus]
[Reaction:9932506] BTRC:CUL1:SKP1:RBX1 binds phosphorylated PER protein [Homo sapiens]
[BlackBoxEvent:9932510] BTRC:CUL1:SKP1:RBX1 (SCF-beta-TrCP1) ubiquitinylates phosphorylated PER1,2,3 [Homo sapiens]
[BlackBoxEvent:9934893] Proteolysis of K48polyUb-K,p-S-PER1,2,3 [Homo sapiens] |
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