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Details on Person Direct control of exocytosis by receptor-mediated activation of the heterotrimeric GTPases Gi and G(o) or by the expression of their active G alpha subunits
| Class:Id | LiteratureReference:400089 |
| _displayName | Direct control of exocytosis by receptor-mediated activation of the heterotrimeric GTPases Gi and G(o) or by the expression of their active G alpha subunits |
| _timestamp | 2009-03-24 02:04:18 |
| author | [Person:264259] Lang, J [Person:400052] Nishimoto, I [Person:400075] Okamoto, T [Person:264296] Regazzi, R [Person:400081] Kiraly, C [Person:264320] Weller, Ulrich [Person:186496] Wollheim, CB |
| created | [InstanceEdit:400084] May, B, 2009-03-24 01:57:51 |
| journal | EMBO J |
| pages | 3635-44 |
| pubMedIdentifier | 7641683 |
| title | Direct control of exocytosis by receptor-mediated activation of the heterotrimeric GTPases Gi and G(o) or by the expression of their active G alpha subunits |
| volume | 14 |
| year | 1995 |
| (literatureReference) | [BlackBoxEvent:265166] Exocytosis of Insulin [Homo sapiens] [Reaction:400037] Gi,Go Heterotrimeric G-protein complex dissociates [Homo sapiens] [Pathway:400042] Adrenaline,noradrenaline inhibits insulin secretion [Homo sapiens] [BlackBoxEvent:400046] L-type Calcium Channels close in pancreatic beta cells [Homo sapiens] [BlackBoxEvent:400063] Low conductance potassium channels in pancreatic beta cells open in response to epinephrine [Homo sapiens] [Reaction:400071] Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline [Homo sapiens] [Reaction:400092] Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins [Homo sapiens] [Reaction:400097] G-beta:G-gamma inhibits Adenylate cyclase [Homo sapiens] [RegulationReference:9642641] Negative regulation by 'Voltage-gated Calcium Channels Type Cav1 (closed) [plasma membrane]' Both G i and G o heterotrimeric G proteins are required to exert the full effect of norepinephrine on the beta-cell K ATP channel [RegulationReference:9642657] Negative regulation by 'G-alpha(i,o):GTP [plasma membrane]' Both G i and G o heterotrimeric G proteins are required to exert the full effect of norepinephrine on the beta-cell K ATP channel |
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No pathways have been reviewed or authored by Direct control of exocytosis by receptor-mediated activation of the heterotrimeric GTPases Gi and G(o) or by the expression of their active G alpha subunits (400089)