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Details on Person Phosphorylation of LIMK-1 by PAK

Class:IdReaction:399952
_displayNamePhosphorylation of LIMK-1 by PAK
_doReleaseTRUE
_timestamp2010-12-02 14:38:55
authored[InstanceEdit:399743] Garapati, P V, 2009-03-23 09:59:28
catalystActivity[CatalystActivity:399948] protein serine/threonine kinase activity of Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:399945] Garapati, P V, 2009-03-23 10:27:02
edited[InstanceEdit:399760] Garapati, P V, 2009-03-23 10:00:07
input[SimpleEntity:113592] ATP [cytosol]
[EntityWithAccessionedSequence:397785] LIMK1 [cytosol] [Homo sapiens]
literatureReference[LiteratureReference:399898] Phosphorylation of cofilin by LIM-kinase is necessary for semaphorin 3A-induced growth cone collapse
[LiteratureReference:399902] Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics
modified[InstanceEdit:416590] Garapati, P V, 2009-03-30 15:26:31
[InstanceEdit:419648] Garapati, P V, 2009-05-05 12:44:47
[InstanceEdit:422117] Garapati, P V, 2009-05-26 10:26:49
[InstanceEdit:422119] Garapati, P V, 2009-05-26 10:52:13
[InstanceEdit:422120] Garapati, P V, 2009-05-26 12:04:08
[InstanceEdit:422121] Garapati, P V, 2009-05-26 12:44:20
[InstanceEdit:422470] Garapati, P V, 2009-05-31 15:13:55
[InstanceEdit:425945] Garapati, P V, 2009-06-09
[InstanceEdit:434703] Matthews, L, 2009-09-02
[InstanceEdit:500204] Garapati, P V, 2010-02-01
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePhosphorylation of LIMK-1 by PAK
output[SimpleEntity:29370] ADP [cytosol]
[EntityWithAccessionedSequence:399816] p-T508-LIMK1 [cytosol] [Homo sapiens]
precedingEvent
releaseDate2009-09-30
reviewed[InstanceEdit:434621] Kumanogoh, A, Kikutani, H, 2009-09-01
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1105352] R-HSA-399952.2
summation[Summation:416568] LIM kinases are serine protein kinases with a unique combina...
(hasEvent)[Pathway:399954] Sema3A PAK dependent Axon repulsion [Homo sapiens]
(precedingEvent)[Reaction:419645] Dimerization of LIMK1 by Hsp90 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9785197] Update Tracker - [Reaction:399952] Phosphorylation of LIMK-1 by PAK - v52:[modifyText]
[_UpdateTracker:9785748] Update Tracker - [Reaction:399952] Phosphorylation of LIMK-1 by PAK - v51:[modifyText]
[_UpdateTracker:9788842] Update Tracker - [Reaction:399952] Phosphorylation of LIMK-1 by PAK - v40:[modifyText]
[_UpdateTracker:9791087] Update Tracker - [Reaction:399952] Phosphorylation of LIMK-1 by PAK - v32:[add_removeOutput, removeInput]
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