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Details on Person Activation of Ca permeable AMPA receptors

Class:Id	Reaction:399712
_displayName	Activation of Ca permeable AMPA receptors
_doRelease	TRUE
_timestamp	2018-05-23 14:31:01
authored	[InstanceEdit:210542] Mahajan, SS, 2008-01-14 16:01:52
catalystActivity	[CatalystActivity:399707] excitatory extracellular ligand-gated monoatomic ion channel activity of Ca permeable AMPA receptor ligand complex [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:399709] Mahajan, SS, 2009-03-19 17:36:34
edited	[InstanceEdit:422465] Mahajan, SS, 2009-05-31 11:49:00 [InstanceEdit:9609392] Orlic-Milacic, Marija, 2018-05-23
input	[SimpleEntity:74112] Ca2+ [extracellular region]
literatureReference	[LiteratureReference:416809] Blockage of Ca(2+)-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells
modified	[InstanceEdit:416812] Mahajan, SS, 2009-04-01 14:59:02 [InstanceEdit:420982] Mahajan, SS, 2009-05-15 16:13:30 [InstanceEdit:421050] Mahajan, SS, 2009-05-15 16:25:42 [InstanceEdit:425688] Matthews, L, 2009-06-05 [InstanceEdit:425735] Gillespie, ME, 2009-06-05 [InstanceEdit:8864975] Jupe, Steve, 2016-03-17 [InstanceEdit:9605730] Orlic-Milacic, Marija, 2018-04-17 [InstanceEdit:9609393] Orlic-Milacic, Marija, 2018-05-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Activation of Ca permeable AMPA receptors
output	[SimpleEntity:74016] Ca2+ [cytosol]
precedingEvent	[Reaction:420977] Ca permeable AMPA receptor ligand binding [Homo sapiens] [Reaction:416320] Trafficking of GluR1-containing AMPA receptors [Homo sapiens] [Reaction:210430] Release of L-Glutamate at the synapse [Homo sapiens] [Reaction:416320] Trafficking of GluR1-containing AMPA receptors [Homo sapiens]
releaseDate	2009-06-24
reviewed	[InstanceEdit:421048] Ziff, EB, 2009-05-15 16:23:37
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105571] R-HSA-399712.5
summation	[Summation:416808] Each AMPA receptor subunit binds one glutamate molecule in t...
(hasEvent)	[Pathway:399710] Activation of AMPA receptors [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9779281] Update Tracker - [Reaction:399712] Activation of Ca permeable AMPA receptors - v66:[removeInput, removeOutput]
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No pathways have been reviewed or authored by Activation of Ca permeable AMPA receptors (399712)