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Details on Person Protease-activated receptors in hemostasis, thrombosis and vascular biology

Class:IdLiteratureReference:397801
_displayNameProtease-activated receptors in hemostasis, thrombosis and vascular biology
_timestamp2009-03-13 13:33:29
author[Person:140086] Coughlin, SR
created[InstanceEdit:397804] Jupe, S, 2009-03-13 13:33:22
journalJ Thromb Haemost
pages1800-14
pubMedIdentifier16102047
titleProtease-activated receptors in hemostasis, thrombosis and vascular biology
volume3
year2005
(literatureReference)[Reaction:114558] Thrombin-activated PARs activate Gq [Homo sapiens]
[Summation:178828] PAR1, 3 and 4 have been shown to directly couple with G12/13...
[Summation:178829] Activated PAR stimulates the G alpha (q) subunit to release ...
[Summation:397840] The classic signalling route for G alpha (q) is activation o...
[Summation:397841] Thrombin activates proteinase activated receptors (PARs) tha...
[Summation:397900] The G12/13 family is probably the least well characterized s...
[Summation:397912] Thrombin recognizes the N-terminal exodomain of PAR1 by inte...
[Summation:398177] PARs can activate heterotrimeric G proteins of the G12/13 an...
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