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Details on Person Thrombin-activated PARs binds G-protein G12/13

Class:Id	Reaction:396941
_displayName	Thrombin-activated PARs binds G-protein G12/13
_doRelease	TRUE
_timestamp	2020-12-02 14:23:21
authored	[InstanceEdit:425201] Akkerman, JW, 2009-06-03
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:396942] Jupe, S, 2009-03-10 13:57:28
edited	[InstanceEdit:870306] Jupe, S, 2010-06-07
inferredFrom	[Reaction:427858] Thrombin-activated PAR binds G-protein G12/13 [Mus musculus]
input	[DefinedSet:114530] Thrombin-activated PARs [plasma membrane] [Homo sapiens] [DefinedSet:398082] G-protein G12/G13 (inactive) [plasma membrane] [Homo sapiens]
modified	[InstanceEdit:398099] Jupe, S, 2009-03-16 17:28:20 [InstanceEdit:400591] Jupe, S, 2009-03-24 10:28:47 [InstanceEdit:400594] Jupe, S, 2009-03-24 10:31:03 [InstanceEdit:400595] Jupe, S, 2009-03-24 10:43:36 [InstanceEdit:400650] Jupe, S, 2009-03-24 16:42:43 [InstanceEdit:416498] Jupe, S, 2009-03-27 14:28:27 [InstanceEdit:421603] Jupe, S, 2009-05-19 09:28:33 [InstanceEdit:427860] Jupe, S, 2009-06-29 [InstanceEdit:435398] Jupe, S, 2009-09-09 [InstanceEdit:453309] Jupe, S, 2010-01-21 [InstanceEdit:456929] Jupe, S, 2010-01-22 [InstanceEdit:870420] Jupe, S, 2010-06-08 [InstanceEdit:9708864] Jassal, Bijay, 2020-12-02 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Thrombin-activated PARs binds G-protein G12/13
output	[Complex:397883] Thrombin activated PAR:G12/13 (inactive) [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:114697] Activated thrombin (factor IIa) cleaves PAR3,4, activating them [Homo sapiens]
releaseDate	2010-09-21
reviewed	[InstanceEdit:870290] Kunapuli, SP, 2010-06-07
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104753] R-HSA-396941.3
summation	[Summation:400602] Thrombin receptors activate G-proteins in the G12/13 family....
(hasEvent)	[Pathway:456926] Thrombin signalling through proteinase activated receptors (PARs) [Homo sapiens]
(precedingEvent)	[Reaction:114552] Thrombin-activated PARs activate G12/13 [Homo sapiens]
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