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Details on Person UniProt:P01103 MYB
Class:Id
ReferenceGeneProduct:393486
_chainChangeLog
chain:1-641 added on Fri February 6 2015
_displayName
UniProt:P01103 MYB
_timestamp
2023-11-03 15:37:58
chain
chain:1-641
checksum
DDDD62BFD3B29187
comment
FUNCTION Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.INTERACTION Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression.DOMAIN Truncation of either the N- or C-terminal of C-Myb leads to increased transformation and transactivation potential.