Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person UniProt:Q9PW71 DUSP4
| Class:Id | ReferenceGeneProduct:393074 |
|---|---|
| _chainChangeLog | chain:1-375 added on Sat February 7 2015 |
| _displayName | UniProt:Q9PW71 DUSP4 |
| _timestamp | 2025-02-21 20:08:31 |
| chain | chain:1-375 |
| checksum | 179290D0C2BEEEF1 |
| comment | FUNCTION Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.CATALYTIC ACTIVITY O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphateCATALYTIC ACTIVITY O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphateCATALYTIC ACTIVITY O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphateSUBCELLULAR LOCATION Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. |
| created | [InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18 |
| description | recommendedName: Dual specificity protein phosphatase 4 ecNumber evidence="1"3.1.3.16 ecNumber evidence="1"3.1.3.48 alternativeName: Mitogen-activated protein kinase phosphatase 2 shortName: MAP kinase phosphatase 2 shortName: MKP-2 |
| geneName | DUSP4 MKP2 |
| identifier | Q9PW71 |
| isSequenceChanged | FALSE |
| keyword | Hydrolase Nucleus Protein phosphatase Reference proteome |
| modified | [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 [InstanceEdit:423310] Kanapin, AA [InstanceEdit:435478] Kanapin, AA [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:8944791] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | DUSP4 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | DUS4_CHICK |
| sequenceLength | 375 |
| species | [Species:49591] Gallus gallus |
| (referenceEntity) | [EntityWithAccessionedSequence:442850] MKP2 [nucleoplasm] [Gallus gallus] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9PW71 DUSP4 (393074)
