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Details on Person Gs activation by prostacyclin receptor

Class:Id	Reaction:392870
_displayName	Gs activation by prostacyclin receptor
_doRelease	TRUE
_timestamp	2017-02-27 14:14:13
authored	[InstanceEdit:425201] Akkerman, JW, 2009-06-03
catalystActivity	[CatalystActivity:432083] guanyl-nucleotide exchange factor activity of Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:392869] Jupe, S, 2009-03-09 15:01:27
edited	[InstanceEdit:870305] Jupe, S, 2010-06-07
input	[SimpleEntity:29438] GTP [cytosol] [Complex:392864] Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:421925] Can a GDP-liganded G-protein be active?
modified	[InstanceEdit:392875] Jupe, S, 2009-03-09 15:23:51 [InstanceEdit:416360] Jupe, S, 2009-03-26 13:50:28 [InstanceEdit:419480] Jupe, S, 2009-05-01 15:24:48 [InstanceEdit:421924] Jupe, S, 2009-05-22 13:40:42 [InstanceEdit:432084] Jupe, S, 2009-08-10 [InstanceEdit:870306] Jupe, S, 2010-06-07 [InstanceEdit:8979622] D'Eustachio, Peter, 2017-02-27 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Gs activation by prostacyclin receptor
output	[SimpleEntity:114549] GDP [plasma membrane] [Complex:392865] Prostacyclin:prostacyclin receptor:G-protein Gs (active) [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:392852] Activated prostacyclin receptor binds G-protein Gs [Homo sapiens] [Reaction:391942] IP receptor can bind prostacyclin [Homo sapiens]
releaseDate	2010-09-21
reviewed	[InstanceEdit:870290] Kunapuli, SP, 2010-06-07
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105056] R-HSA-392870.3
summation	[Summation:391991] The G-protein alpha subunit exchanges GDP for GTP
(hasEvent)	[Pathway:392851] Prostacyclin signalling through prostacyclin receptor [Homo sapiens]
(precedingEvent)	[Reaction:392874] Dissociation of the Prostacyclin receptor:Gs complex [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9781515] Update Tracker - [Reaction:392870] Gs activation by prostacyclin receptor - v60:[add_removeInput]
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No pathways have been reviewed or authored by Gs activation by prostacyclin receptor (392870)