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Details on Person Ptk2 autophosphorylates at Y397

Class:IdReaction:3928599
_displayNamePtk2 autophosphorylates at Y397
_doReleaseTRUE
_timestamp2017-07-12 18:14:56
authored[InstanceEdit:3928653] Garapati, P V, 2013-07-22
catalystActivity[CatalystActivity:3928587] protein tyrosine kinase activity of ephrin-B2:Ephb2:FAK1 [plasma membrane]
catalystActivityReference[CatalystActivityReference:9644012] protein tyrosine kinase activity of ephrin-B2:Ephb2:FAK1 [plasma membrane] EphB receptors regulate dendritic spine morphogenesis through the recruitment/phosphorylation of focal adhesion kinase and RhoA activation
compartment[Compartment:876] plasma membrane
[Compartment:70101] cytosol
created[InstanceEdit:3928638] Garapati, P V, 2013-07-22
edited[InstanceEdit:3928653] Garapati, P V, 2013-07-22
entityOnOtherCell[EntityWithAccessionedSequence:3928450] Ephrin-B2 [plasma membrane] [Mus musculus]
input[SimpleEntity:113592] ATP [cytosol]
[Complex:3928557] ephrin-B2:Ephb2:FAK1 [plasma membrane] [Mus musculus]
isChimericFALSE
literatureReference[LiteratureReference:3928042] Focal adhesion kinase acts downstream of EphB receptors to maintain mature dendritic spines by regulating cofilin activity
[LiteratureReference:3928044] EphB receptors regulate dendritic spine morphogenesis through the recruitment/phosphorylation of focal adhesion kinase and RhoA activation
[LiteratureReference:372615] Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src
modified[InstanceEdit:4640897] Garapati, P V, 2013-09-27
[InstanceEdit:5096527] Garapati, P V, 2013-11-11
[InstanceEdit:5096559] Garapati, P V, 2013-11-11
[InstanceEdit:5097236] Garapati, P V, 2013-11-11
[InstanceEdit:5099816] Garapati, P V, 2013-11-12
[InstanceEdit:5144541] Garapati, P V, 2013-11-18
[InstanceEdit:5490336] Garapati, P V, 2014-05-19
[InstanceEdit:9012335] D'Eustachio, Peter, 2017-07-12
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePtk2 autophosphorylates at Y397
output[SimpleEntity:29370] ADP [cytosol]
[Complex:3928508] ephrin-B2:Ephb2:p-Y428-FAK1 [plasma membrane] [Mus musculus]
releaseDate2014-06-10
reviewed[InstanceEdit:5490284] Ip, Nancy Y, 2014-05-19
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48892] Mus musculus
stableIdentifier[StableIdentifier:5644727] R-MMU-3928599.4
summation[Summation:3928290] Focal adhesion kinase 1 (PTK2, FAK, FAK1) activation plays a...
(inferredFrom)[Reaction:3928610] PTK2 autophosphorylates at Y397 [Homo sapiens]
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No pathways have been reviewed or authored by Ptk2 autophosphorylates at Y397 (3928599)