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Details on Person N-WASP binds ARP2/3 and G-actin

Class:Id	Reaction:3928595
_displayName	N-WASP binds ARP2/3 and G-actin
_doRelease	TRUE
_timestamp	2014-11-20 02:56:34
authored	[InstanceEdit:3928653] Garapati, P V, 2013-07-22
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:3928638] Garapati, P V, 2013-07-22
edited	[InstanceEdit:3928653] Garapati, P V, 2013-07-22
entityOnOtherCell	[DefinedSet:3928378] EFNBs [plasma membrane] [Homo sapiens]
input	[Complex:1861670] ARP2/3 complex (ATP bound) [cytosol] [Homo sapiens] [Complex:3928536] p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] [Homo sapiens] [Complex:201857] G-actin [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:442576] Different WASP family proteins stimulate different Arp2/3 complex-dependent actin-nucleating activities [LiteratureReference:442552] The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly
modified	[InstanceEdit:4443762] Garapati, P V, 2013-09-03 [InstanceEdit:4640897] Garapati, P V, 2013-09-27 [InstanceEdit:5096527] Garapati, P V, 2013-11-11 [InstanceEdit:5096559] Garapati, P V, 2013-11-11 [InstanceEdit:5097236] Garapati, P V, 2013-11-11 [InstanceEdit:5099816] Garapati, P V, 2013-11-12 [InstanceEdit:5144541] Garapati, P V, 2013-11-18 [InstanceEdit:5490336] Garapati, P V, 2014-05-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	N-WASP binds ARP2/3 and G-actin
output	[Complex:3928519] p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:3928601] CDC42 and PIP2 bind WASL, activating it [Homo sapiens] [Reaction:3928632] ITSN1 exchanges GTP for GDP on CDC42, activating it [Homo sapiens]
releaseDate	2014-06-10
reviewed	[InstanceEdit:5490284] Ip, Nancy Y, 2014-05-19
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5645163] R-HSA-3928595.2
summation	[Summation:3928283] Once neural Wiskott-Aldrich syndrome protein (WASL, N-WASP) ...
(hasEvent)	[Pathway:3928662] EPHB-mediated forward signaling [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9846757] Update Tracker - [Reaction:3928595] N-WASP binds ARP2/3 and G-actin - v84:[modifyText]
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