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Details on Person Myosin II regulatory light chain (MLC) acts downstream of se...

Class:IdSummation:3928270
_displayNameMyosin II regulatory light chain (MLC) acts downstream of se...
_timestamp2013-09-27 14:43:23
created[InstanceEdit:3928288] Garapati, P V, 2013-07-22
modified[InstanceEdit:4640880] Garapati, P V, 2013-09-27
textMyosin II regulatory light chain (MLC) acts downstream of serine/threonine-protein kinase PAK (PAK) to mediate its effect on spine morphogenesis and excitatory synapse formation. PAK directly phosphorylates MLC on serine 19. MLC phosphorylation could promote dendritic spine morphogenesis by stabilizing the actin network at this site (Zhang et al. 2005).
(summation)[Reaction:3928640] PAKs phosphorylate MLC [Homo sapiens]
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