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Details on Person Focal adhesion kinase acts downstream of EphB receptors to maintain mature dendritic spines by regulating cofilin activity

Class:IdLiteratureReference:3928042
_displayNameFocal adhesion kinase acts downstream of EphB receptors to maintain mature dendritic spines by regulating cofilin activity
_timestamp2013-07-22 14:55:26
author[Person:3214904] Shi, Yang
[Person:3928259] Pontrello, Crystal G
[Person:3927996] DeFea, Kathryn A
[Person:3928178] Reichardt, Louis F
[Person:3928184] Ethell, Iryna M
created[InstanceEdit:3928156] Garapati, P V, 2013-07-22
journalJ. Neurosci.
pages8129-42
pubMedIdentifier19553453
titleFocal adhesion kinase acts downstream of EphB receptors to maintain mature dendritic spines by regulating cofilin activity
volume29
year2009
(literatureReference)[Summation:3928290] Focal adhesion kinase 1 (PTK2, FAK, FAK1) activation plays a...
[Summation:3928303] Focal adhesion kinase 1 (PTK2, FAK, FAK1) acts downstream of...
[Summation:3928315] The EPHB2-FAK pathway partially promotes dendritic spine sta...
[Summation:3928316] Multiple EPHB receptors contribute directly to dendritic spi...
[Reaction:3928576] RHOA:GTP binds ROCK, activating it [Homo sapiens]
[Reaction:3928599] Ptk2 autophosphorylates at Y397 [Mus musculus]
[Reaction:3928630] EphBs binds Ptk2 [Mus musculus]
[CatalystActivityReference:9644012] protein tyrosine kinase activity of ephrin-B2:Ephb2:FAK1 [plasma membrane] EphB receptors regulate dendritic spine morphogenesis through the recruitment/phosphorylation of focal adhesion kinase and RhoA activation
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