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Details on Person Transport of L1 into endosomes

Class:Id	Reaction:392749
_displayName	Transport of L1 into endosomes
_doRelease	TRUE
_timestamp	2010-12-02 14:39:49
authored	[InstanceEdit:374671] Garapati, P V, 2008-07-30 10:22:58
compartment	[Compartment:17940] endosome
created	[InstanceEdit:392750] Garapati, P V, 2009-03-07 11:31:09
edited	[InstanceEdit:374671] Garapati, P V, 2008-07-30 10:22:58
input	[Complex:392743] L1:AP-2 Clathrin complex [clathrin-coated endocytic vesicle] [Homo sapiens]
literatureReference	[LiteratureReference:392731] The neural cell adhesion molecule L1 interacts with the AP-2 adaptor and is endocytosed via the clathrin-mediated pathway [LiteratureReference:392728] Recycling of the cell adhesion molecule L1 in axonal growth cones [LiteratureReference:549057] Endocytosis of beta1 integrins is an early event in migration promoted by the cell adhesion molecule L1
modified	[InstanceEdit:445093] Garapati, P V, 2009-10-27 [InstanceEdit:446625] Garapati, P V, 2009-11-16 [InstanceEdit:447049] Garapati, P V, 2009-11-19 [InstanceEdit:447051] Garapati, P V, 2009-11-19 [InstanceEdit:448355] Garapati, P V, 2009-11-24 [InstanceEdit:513003] Garapati, P V, 2010-02-16 [InstanceEdit:532606] Garapati, P V, 2010-03-01 [InstanceEdit:549059] Garapati, P V, 2010-03-16 [InstanceEdit:750980] Garapati, P V, 2010-05-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Transport of L1 into endosomes
output	[Complex:392746] L1:AP-2 Clathrin complex [endosome] [Homo sapiens]
precedingEvent	[Reaction:392748] L1 binds to AP-2 Clathrin complex [Homo sapiens] [Reaction:445089] Dephosphorylation of pL1 (Y1176) [Homo sapiens]
releaseDate	2010-06-15
reviewed	[InstanceEdit:513001] Maness, PF, 2010-02-16
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105533] R-HSA-392749.2
summation	[Summation:392733] Membrane bound L1 is internalized through clathrin coated ve...
(hasEvent)	[Pathway:437239] Recycling pathway of L1 [Homo sapiens]
(precedingEvent)	[Reaction:374696] Phosphorylation of L1 by p90rsk [Homo sapiens] [Reaction:445077] Transport of L1 from C-domain to P-domain [Homo sapiens] [Reaction:445079] Phosphorylation of L1 by ERK [Homo sapiens]
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No pathways have been reviewed or authored by Transport of L1 into endosomes (392749)