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Details on Person TP receptor can bind thromboxane

Class:Id	Reaction:391939
_displayName	TP receptor can bind thromboxane
_doRelease	TRUE
_timestamp	2010-12-02 14:33:09
authored	[InstanceEdit:416886] Jassal, Bijay, 2009-04-02
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:391938] Jassal, Bijay, 2009-02-25
edited	[InstanceEdit:416886] Jassal, Bijay, 2009-04-02
input	[EntityWithAccessionedSequence:391837] TBXA2R [plasma membrane] [Homo sapiens] [SimpleEntity:391932] TXA2 [extracellular region]
literatureReference	[LiteratureReference:416937] Cloning and expression of cDNA for a human thromboxane A2 receptor [LiteratureReference:416867] The human thromboxane A2 receptor alpha isoform (TP alpha) functionally couples to the G proteins Gq and G11 in vivo and is activated by the isoprostane 8-epi prostaglandin F2 alpha
modified	[InstanceEdit:391944] Jassal, Bijay, 2009-02-25 [InstanceEdit:416886] Jassal, Bijay, 2009-04-02 [InstanceEdit:416950] Jassal, Bijay, 2009-04-02 [InstanceEdit:420852] Jassal, Bijay, 2009-05-14 [InstanceEdit:420853] Jassal, Bijay, 2009-05-14 [InstanceEdit:422124] Jassal, Bijay, 2009-05-26 [InstanceEdit:422382] Jassal, Bijay, 2009-05-29 [InstanceEdit:532503] Jupe, S, 2010-03-01 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TP receptor can bind thromboxane
output	[Complex:391925] TBXA2R:TXA2 [plasma membrane] [Homo sapiens]
releaseDate	2009-06-24
reviewed	[InstanceEdit:422381] D'Eustachio, P, 2009-05-29 07:44:22
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104277] R-HSA-391939.2
summation	[Summation:416896] Thromboxane (TBXA2) is a potent stimulator for platelet aggr...
(hasEvent)	[Pathway:391908] Prostanoid ligand receptors [Homo sapiens] [Pathway:428930] Thromboxane signalling through TP receptor [Homo sapiens]
(precedingEvent)	[Reaction:428749] Activated TP receptor binds G-proten Gq [Homo sapiens] [Reaction:428909] Activated TP receptor binds G-protein G13 [Homo sapiens] [Reaction:751027] Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9790374] Update Tracker - [Reaction:391939] TP receptor can bind thromboxane - v33:[modifyText]
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No pathways have been reviewed or authored by TP receptor can bind thromboxane (391939)