Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person The 5-HT4 receptor (Van den Wyngaert I et al, 1997) is locat...
| Class:Id | Summation:390977 |
|---|---|
| _displayName | The 5-HT4 receptor (Van den Wyngaert I et al, 1997) is locat... |
| _timestamp | 2009-02-12 14:44:06 |
| created | [InstanceEdit:390935] Jassal, Bijay, 2009-02-12 |
| text | The 5-HT4 receptor (Van den Wyngaert I et al, 1997) is located in the alimentary tract, bladder, heart and adrenal gland as well as the central nervous system (CNS). It modulates the release of various neurotransmitters. Multiple transcripts encode proteins with distinct C-terminal sequences, but the full-length nature of some transcript variants has not been determined (Blondel O et al, 1998). The 5-HT6 receptor (Kohen R et al, 1996) is primarily expressed in the brain and is involved in glutamatergic and cholinergic neuronal activity. The 5-HT7 receptor (Stam NJ et al, 1997) plays a role in vasculature smooth muscle relaxation and in the GI tract. It is involved in thermoregulation, circadian rhythm, learning and memory, and sleep. All these receptor types mediate their actions by coupling to the G protein alpha-s subtype, which increases cellular cAMP levels (Baker LP et al, 1998; Zhang JY et al, 2003). |
| (summation) | [Reaction:390931] 5-HT4, 6 and 7 receptors can bind serotonin [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by The 5-HT4 receptor (Van den Wyngaert I et al, 1997) is locat... (390977)
