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Details on Person 5-HT4, 6 and 7 receptors can bind serotonin

Class:Id	Reaction:390931
_displayName	5-HT4, 6 and 7 receptors can bind serotonin
_doRelease	TRUE
_timestamp	2010-03-01 12:56:57
authored	[InstanceEdit:390928] Jassal, Bijay, 2009-02-12
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:390928] Jassal, Bijay, 2009-02-12
edited	[InstanceEdit:390928] Jassal, Bijay, 2009-02-12
input	[DefinedSet:390942] HTR4,6,7 [plasma membrane] [Homo sapiens] [SimpleEntity:114523] 5HT [extracellular region]
literatureReference	[LiteratureReference:391009] Cloning, expression, and pharmacology of four human 5-hydroxytryptamine 4 receptor isoforms produced by alternative splicing in the carboxyl terminus [LiteratureReference:391025] Cloning and expression of a human serotonin 5-HT4 receptor cDNA [LiteratureReference:390980] Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor [LiteratureReference:390966] Human serotonin 5-HT7 receptor: cloning and pharmacological characterisation of two receptor variants [LiteratureReference:391036] Characterization of the 5-HT6 receptor coupled to Ca2+ signaling using an enabling chimeric G-protein [LiteratureReference:391019] Stimulation of type 1 and type 8 Ca2+/calmodulin-sensitive adenylyl cyclases by the Gs-coupled 5-hydroxytryptamine subtype 5-HT7A receptor
modified	[InstanceEdit:390935] Jassal, Bijay, 2009-02-12 [InstanceEdit:392160] Jassal, Bijay, 2009-02-27 [InstanceEdit:392260] Jassal, Bijay, 2009-03-02 [InstanceEdit:420853] Jassal, Bijay, 2009-05-14 [InstanceEdit:422382] Jassal, Bijay, 2009-05-29 [InstanceEdit:432970] Jassal, Bijay, 2009-08-18 [InstanceEdit:532503] Jupe, S, 2010-03-01 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	5-HT4, 6 and 7 receptors can bind serotonin
output	[Complex:390972] HTR4,6,7:5HT [plasma membrane] [Homo sapiens]
releaseDate	2009-04-01
reviewed	[InstanceEdit:392262] D'Eustachio, P, 2009-03-02 09:24:35
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:398468] R-HSA-390931.2
summation	[Summation:390977] The 5-HT4 receptor (Van den Wyngaert I et al, 1997) is locat...
(hasEvent)	[Pathway:390666] Serotonin receptors [Homo sapiens]
(precedingEvent)	[Reaction:744887] Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs [Homo sapiens] [Reaction:9660828] ADORA2B:Ade-Rib binds heterometric G-protein Gs [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9791400] Update Tracker - [Reaction:390931] 5-HT4, 6 and 7 receptors can bind serotonin - v30:[add_removeInput]
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No pathways have been reviewed or authored by 5-HT4, 6 and 7 receptors can bind serotonin (390931)