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Details on Person Post-translational modifications of MYLK down-regulate its e...

Class:IdSummation:390709
_displayNamePost-translational modifications of MYLK down-regulate its e...
_timestamp2009-02-10 10:32:00
created[InstanceEdit:390712] Garapati, P V, 2009-02-10 10:31:48
literatureReference[LiteratureReference:376092] Phosphorylation of myosin light chain kinase by p21-activated kinase PAK2
textPost-translational modifications of MYLK down-regulate its enzyme activity and suppress RLC phosphorylation and its activation. PAK catalyzes MYLK phosphorylation on serine residues 439 and 991 and this phosphorylation prevents the binding of Ca++/Calmodulin and activation of MYLK.
(summation)[Reaction:376143] Phosphorylation of MYLK by PAK2 [Homo sapiens]
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No pathways have been reviewed or authored by Post-translational modifications of MYLK down-regulate its e... (390709)