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Details on Person ADRB1 bind ADR,NAd

Class:Id	Reaction:390674
_displayName	ADRB1 bind ADR,NAd
_doRelease	TRUE
_timestamp	2024-03-07 02:46:16
authored	[InstanceEdit:390626] Jassal, Bijay, 2009-02-10
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:390626] Jassal, Bijay, 2009-02-10
edited	[InstanceEdit:390626] Jassal, Bijay, 2009-02-10
input	[EntityWithAccessionedSequence:390653] ADRB1 [plasma membrane] [Homo sapiens] [DefinedSet:390627] ADR, NAd [extracellular region]
literatureReference	[LiteratureReference:390780] Cloning of the cDNA for the human beta 1-adrenergic receptor [LiteratureReference:390785] cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor [LiteratureReference:390792] Molecular characterization of the human beta 3-adrenergic receptor [LiteratureReference:390777] Similarities and differences in the coupling of human beta1- and beta2-adrenoceptors to Gs(alpha) splice variants
modified	[InstanceEdit:390782] Jassal, Bijay, 2009-02-10 [InstanceEdit:392160] Jassal, Bijay, 2009-02-27 [InstanceEdit:392260] Jassal, Bijay, 2009-03-02 [InstanceEdit:420853] Jassal, Bijay, 2009-05-14 [InstanceEdit:422382] Jassal, Bijay, 2009-05-29 [InstanceEdit:532503] Jupe, S, 2010-03-01 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:9609318] Jassal, Bijay, 2018-05-21 [InstanceEdit:9611731] Jassal, Bijay, 2018-06-19 [InstanceEdit:9611854] Jassal, Bijay, 2018-06-21 [InstanceEdit:9611924] Jassal, Bijay, 2018-06-22 [InstanceEdit:9617275] Jassal, Bijay, 2018-08-21 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9864372] Orlic-Milacic, Marija, 2024-03-07
name	ADRB1 bind ADR,NAd Beta-1 adrenoceptors bind catecholamines
output	[Complex:390643] ADRB1:ADR,NAd [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:9611751] β1,2-agonists bind ADRB1,2 [Homo sapiens] [Reaction:9611721] β1-agonists bind ADRB1 [Homo sapiens]
regulatedBy	[NegativeRegulation:9609304] Negative regulation by 'ADRB1,2,3:β-blockers [plasma membrane]' [PositiveRegulation:9611737] Positive regulation by 'β1,2-agonists:ADBR1,2 [plasma membrane]' [PositiveRegulation:9611927] Positive regulation by 'β1-agonists:ADBR1 [plasma membrane]'
releaseDate	2009-04-01
reviewed	[InstanceEdit:392262] D'Eustachio, P, 2009-03-02 09:24:35
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:398323] R-HSA-390674.4
summation	[Summation:390783] β-adrenergic receptors couple with G protein alpha-s subtype...
(hasEvent)	[Pathway:390696] Adrenoceptors [Homo sapiens]
(precedingEvent)	[Reaction:744887] Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs [Homo sapiens] [Reaction:8982645] GRKs bind ADRB2:Catecholamine [Homo sapiens] [Reaction:9660828] ADORA2B:Ade-Rib binds heterometric G-protein Gs [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9779068] Update Tracker - [Reaction:390674] ADRB1 bind ADR,NAd - v66:[addRegulator, add_removeInput, modifyText]
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No pathways have been reviewed or authored by ADRB1 bind ADR,NAd (390674)