Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person WTS binds to SAV

Class:IdReaction:390087
_displayNameWTS binds to SAV
_doReleaseTRUE
_timestamp2017-08-10 16:10:15
authored[InstanceEdit:390144] Williams, MG, 2009-01-23 09:43:46
compartment[Compartment:70101] cytosol
created[InstanceEdit:390104] Williams, MG, 2009-01-23 09:54:10
edited[InstanceEdit:390104] Williams, MG, 2009-01-23 09:54:10
figure[Figure:451867] /figures/DrosBHippoW05.jpg
input[Complex:451812] HPO dimer:SAV [cytosol] [Drosophila melanogaster]
[EntityWithAccessionedSequence:390037] WTS [cytosol] [Drosophila melanogaster]
literatureReference[LiteratureReference:390188] The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila
[LiteratureReference:390106] salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
[LiteratureReference:390080] hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
[LiteratureReference:390123] The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis
modified[InstanceEdit:451804] Williams, MG, 2010-01-14
[InstanceEdit:909539] Williams, MG, 2010-07-07
[InstanceEdit:912304] Williams, MG, 2010-07-08
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:9015640] D'Eustachio, Peter, 2017-08-10
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameWTS binds to SAV
output[Complex:451836] HPO dimer:SAV:WTS [cytosol] [Drosophila melanogaster]
precedingEvent
releaseDate2010-07-23
reviewed[InstanceEdit:909538] Irvine, KD, 2009-11-25
reviewStatus[ReviewStatus:9821382] five stars
species[Species:56210] Drosophila melanogaster
stableIdentifier[StableIdentifier:8910449] R-DME-390087.2
summation[Summation:390186] The serine/threonine kinase, Warts (WTS), binds to the WW do...
(hasEvent)[Pathway:390089] Formation of the Hippo kinase cassette [Drosophila melanogaster]
(precedingEvent)[Reaction:390124] MATS binds to HPO dimer [Drosophila melanogaster]
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