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Details on Person Peroxisomal HSD17B4 dimer catalyzes the reaction of trans-2,...
| Class:Id | Summation:389998 |
|---|---|
| _displayName | Peroxisomal HSD17B4 dimer catalyzes the reaction of trans-2,... |
| _timestamp | 2024-06-19 22:22:16 |
| created | [InstanceEdit:389984] D'Eustachio, P, 2009-01-21 23:05:37 |
| modified | [InstanceEdit:390001] D'Eustachio, P, 2009-01-21 23:06:24 [InstanceEdit:9914019] D'Eustachio, Peter, 2024-06-19 |
| text | Peroxisomal HSD17B4 dimer catalyzes the reaction of trans-2,3-dehydropristanoyl-CoA and H2O to form 3-hydroxypristanoyl-CoA. The enzyme is bifunctional - an aminoterminal domain catalyzes the dehydrogenation of a variety of 3-hydroxyacyl-CoA's and a carboxyterminal domain catalyzes the hydration of a variety of trans-2,3-dehydroacyl-CoA's, the reaction annotated here (Ferdinandusse et al. 2004; Jiang et al. 1996, 1997). Defects in the enzyme are associated with a severe disorder of peroxisomal fatty acid metabolism in humans (Ferdinandusse et al. 2006). |
| (summation) | [Reaction:389986] trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA [Homo sapiens] |
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No pathways have been reviewed or authored by Peroxisomal HSD17B4 dimer catalyzes the reaction of trans-2,... (389998)
