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Details on Person Beta-tubulin:GTP + Cofactor D -> Beta-tubulin:GTP: Cofactor D

Class:Id	Reaction:389969
_displayName	Beta-tubulin:GTP + Cofactor D -> Beta-tubulin:GTP: Cofactor D
_doRelease	TRUE
_timestamp	2015-02-11 13:14:52
authored	[InstanceEdit:387111] Matthews, L, 2008-12-01 04:46:41
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:389975] Matthews, L, 2009-01-21 19:24:07
edited	[InstanceEdit:391462] Matthews, L, 2009-02-21 05:37:28
figure	[Figure:392785] /figures/Tub4.png
inferredFrom	[Reaction:391520] Beta-tubulin:GTP + Cofactor D -> Beta-tubulin:GTP: Cofactor D [Bos taurus]
input	[Complex:391246] GTP:beta-tubulin folding intermediate [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:379540] TBCD [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:5250227] Effect of TBCD and its regulatory interactor Arl2 on tubulin and microtubule integrity [LiteratureReference:5250199] ADP ribosylation factor-like protein 2 (Arl2) regulates the interaction of tubulin-folding cofactor D with native tubulin
modified	[InstanceEdit:391238] Matthews, L, 2009-02-17 02:23:01 [InstanceEdit:391506] Matthews, L, 2009-02-23 07:54:53 [InstanceEdit:391969] Matthews, L, 2009-02-25 17:30:26 [InstanceEdit:391987] Matthews, L, 2009-02-26 14:15:02 [InstanceEdit:392114] Matthews, L, 2009-02-27 06:02:18 [InstanceEdit:392146] Matthews, L, 2009-02-27 13:19:39 [InstanceEdit:392147] Matthews, L, 2009-02-27 13:30:21 [InstanceEdit:392314] Matthews, L, 2009-03-02 17:53:14 [InstanceEdit:392480] Matthews, L, 2009-03-04 17:45:55 [InstanceEdit:392773] Matthews, L, 2009-03-08 07:09:40 [InstanceEdit:5250224] Jassal, Bijay, 2014-01-24 [InstanceEdit:5674209] Jassal, Bijay, 2015-02-11 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Beta-tubulin:GTP + Cofactor D -> Beta-tubulin:GTP: Cofactor D
output	[Complex:391245] Cofactor D:GTP:beta tubulin [cytosol] [Homo sapiens]
precedingEvent	[Reaction:389954] Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC [Homo sapiens] [Reaction:389961] ADP is exchanged for ATP in the (ADP:CCT/TriC):tubulin complex [Homo sapiens]
regulatedBy	[NegativeRegulation:5255416] Negative regulation by 'ARL2 [cytosol]'
releaseDate	2009-04-01
reviewed	[InstanceEdit:389965] Cowan, NJ, 2009-01-21 16:47:24
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:5674206] Jassal, Bijay, 2015-02-11
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:398453] R-HSA-389969.3
summation	[Summation:391528] Beta-tubulin folding intermediates generated via ATP-depende...
(hasEvent)	[Pathway:389977] Post-chaperonin tubulin folding pathway [Homo sapiens]
(precedingEvent)	[Reaction:389976] Beta-tubulin:GTP:Cofactor D+alpha-tubulin:GTP:Cofactor E-> Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9786793] Update Tracker - [Reaction:389969] Beta-tubulin:GTP + Cofactor D -> Beta-tubulin:GTP: Cofactor D - v48:[addLiteratureReference, addRegulator, modifyText]
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No pathways have been reviewed or authored by Beta-tubulin:GTP + Cofactor D -> Beta-tubulin:GTP: Cofactor D (389969)