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Details on Person ALDH3A2-2 oxidizes pristanal to pristanate

Class:IdReaction:389609
_displayNameALDH3A2-2 oxidizes pristanal to pristanate
_doReleaseTRUE
_timestamp2024-08-02 16:00:25
authored[InstanceEdit:389624] D'Eustachio, P, 2009-01-10 20:36:15
catalystActivity[CatalystActivity:6811622] aldehyde dehydrogenase (NAD+) activity of ALDH3A2-2 dimer [peroxisomal membrane]
compartment[Compartment:17951] peroxisomal matrix
created[InstanceEdit:389592] D'Eustachio, P, 2009-01-10 20:38:44
crossReference[DatabaseIdentifier:9913888] RHEA:44017
edited[InstanceEdit:389624] D'Eustachio, P, 2009-01-10 20:36:15
input[SimpleEntity:192307] NAD+ [peroxisomal matrix]
[SimpleEntity:389636] Pristanal [peroxisomal matrix]
[SimpleEntity:141343] H2O [peroxisomal matrix]
internalReviewed[InstanceEdit:9914192] D'Eustachio, Peter, 2024-06-21
[InstanceEdit:9914195] D'Eustachio, Peter, 2024-06-21
literatureReference[LiteratureReference:6811625] Dual subcellular localization in the endoplasmic reticulum and peroxisomes and a vital role in protecting against oxidative stress of fatty aldehyde dehydrogenase are achieved by alternative splicing
[LiteratureReference:389626] Identification of pristanal dehydrogenase activity in peroxisomes: conclusive evidence that the complete phytanic acid alpha-oxidation pathway is localized in peroxisomes
[LiteratureReference:6811626] Monitoring of fatty aldehyde dehydrogenase by formation of pyrenedecanoic acid from pyrenedecanal
[LiteratureReference:6811619] Human liver fatty aldehyde dehydrogenase: microsomal localization, purification, and biochemical characterization
[LiteratureReference:6811618] Fatty aldehyde dehydrogenase: genomic structure, expression and mutation analysis in Sjögren-Larsson syndrome
modified[InstanceEdit:389800] D'Eustachio, P, 2009-01-16 16:46:20
[InstanceEdit:392189] D'Eustachio, P, 2009-02-27 15:24:50
[InstanceEdit:6811613] D'Eustachio, Peter, 2015-11-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9913870] D'Eustachio, Peter, 2024-06-18
[InstanceEdit:9914193] D'Eustachio, Peter, 2024-06-21
[InstanceEdit:9914196] D'Eustachio, Peter, 2024-06-21
[InstanceEdit:9917351] D'Eustachio, Peter, 2024-08-02
nameALDH3A2-2 oxidizes pristanal to pristanate
pristanal + NAD+ => pristanate + NADH + H+
2,6,10,14-tetramethylpentadecanal + H2O + NAD(+) => 2,6,10,14-tetramethylpentadecanoate + 2 H(+) + NADH
output[SimpleEntity:6811612] pristanate [peroxisomal matrix]
[SimpleEntity:192305] NADH [peroxisomal matrix]
[SimpleEntity:193465] H+ [peroxisomal matrix]
[SimpleEntity:193465] H+ [peroxisomal matrix]
precedingEvent
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2009-04-01
reviewed[InstanceEdit:392190] Jassal, Bijay, 2009-02-27
[InstanceEdit:9917333] Hill, David P, 2024-08-02
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:398348] R-HSA-389609.4
structureModified[InstanceEdit:9913870] D'Eustachio, Peter, 2024-06-18
summation[Summation:389610] Peroxisomal ALDH3A2-2 (fatty aldehyde dehydrogenase family 3...
(hasEvent)[Pathway:389599] Alpha-oxidation of phytanate [Homo sapiens]
(precedingEvent)[Reaction:389632] pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate [Homo sapiens]
(updatedInstance)[_UpdateTracker:9783733] Update Tracker - [Reaction:389609] ALDH3A2-2 oxidizes pristanal to pristanate - v56:[addLiteratureReference, add_removeCatalystActivity, add_removeOutput, modifyText]
[_UpdateTracker:9919469] Update Tracker - [Reaction:389609] ALDH3A2-2 oxidizes pristanal to pristanate - v90:[removeInput]
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