Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person Thrombin (Butkowski RJ et al, 1977) plays a vital role in bl...
| Class:Id | Summation:389401 |
|---|---|
| _displayName | Thrombin (Butkowski RJ et al, 1977) plays a vital role in bl... |
| _timestamp | 2009-01-07 14:39:00 |
| created | [InstanceEdit:389485] Jassal, B, 2009-01-07 14:37:24 |
| text | Thrombin (Butkowski RJ et al, 1977) plays a vital role in blood homeostasis, inflammation and wound healing. Thrombin (which cleaves bonds after arginine and lysine) converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII. Complexed with thrombomodulin it can also activate protein C. It performs these functions by binding to four proteinase-activated receptors (PAR1-4) (Kahn ML, et al, 1999; Bohm SK et al, 1996). These complexes couple to G proteins which stimulate phosphoinositide hydrolysis. |
| (summation) | [Reaction:389463] Proteinase-activated receptors can bind thrombin [Homo sapiens] |
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No pathways have been reviewed or authored by Thrombin (Butkowski RJ et al, 1977) plays a vital role in bl... (389401)
