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Details on Person PI3K binds CD28

Class:IdReaction:388832
_displayNamePI3K binds CD28
_doReleaseTRUE
_timestamp2024-11-08 09:16:14
authored[InstanceEdit:388810] Garapati, P V, 2008-12-16 11:12:19
[InstanceEdit:9927528] Garapati, Phani Vijay, 2024-11-07
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:388834] Garapati, P V, 2008-12-16 11:22:12
edited[InstanceEdit:388810] Garapati, P V, 2008-12-16 11:12:19
input[Complex:388777] phospho CD28:B7-1/B7-2 [plasma membrane] [Homo sapiens]
[CandidateSet:9927349] Class 1A PI3Ks [cytosol] [Homo sapiens]
literatureReference[LiteratureReference:388671] Two distinct intracytoplasmic regions of the T-cell adhesion molecule CD28 participate in phosphatidylinositol 3-kinase association
[LiteratureReference:389297] The PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3
modified[InstanceEdit:389162] Garapati, P V, 2008-12-22 11:21:44
[InstanceEdit:389355] Garapati, P V, 2009-01-06 13:43:15
[InstanceEdit:392682] Garapati, P V, 2009-03-06 16:22:43
[InstanceEdit:392695] Garapati, P V, 2009-03-06 16:43:16
[InstanceEdit:398061] Garapati, P V, 2009-03-16 14:12:16
[InstanceEdit:398109] Garapati, P V, 2009-03-16 18:08:29
[InstanceEdit:422361] D'Eustachio, P, 2009-05-28 17:55:23
[InstanceEdit:422525] Garapati, P V, 2009-06-01 19:13:02
[InstanceEdit:425945] Garapati, P V, 2009-06-09
[InstanceEdit:434703] Matthews, L, 2009-09-02
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9927359] Tiwari, Krishna, 2024-11-05
[InstanceEdit:9927591] Tiwari, Krishna, 2024-11-08
namePI3K binds CD28
output[Complex:388783] CD28:PI3K [plasma membrane] [Homo sapiens]
precedingEvent
previousReviewStatus[ReviewStatus:9821384] two stars
releaseDate2009-09-30
reviewed[InstanceEdit:422514] Bluestone, JA, Esensten, J, 2009-06-01 18:47:33
[InstanceEdit:9927531] Matthews, Lisa, 2024-11-07
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1105878] R-HSA-388832.3
structureModified[InstanceEdit:9927359] Tiwari, Krishna, 2024-11-05
summation[Summation:388722] The phosphorylated YMNM motif in CD28 interacts with the Src...
(hasEvent)[Pathway:389357] CD28 dependent PI3K/Akt signaling [Homo sapiens]
(precedingEvent)[Reaction:389158] CD28 bound PI3K phosphorylates PIP2 to PIP3 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9928406] Update Tracker - [Reaction:388832] PI3K binds CD28 - v91:[add_removeInput, modifyText]
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No pathways have been reviewed or authored by PI3K binds CD28 (388832)
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