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Details on Person Initiation of SAHF formation

Class:IdReaction:3878123
_displayNameInitiation of SAHF formation
_doReleaseTRUE
_timestamp2013-09-05 11:37:54
authored[InstanceEdit:3900006] Orlic-Milacic, M, 2013-07-15
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:3878124] Orlic-Milacic, M, 2013-07-12
edited[InstanceEdit:3901124] D'Eustachio, P, 2013-07-15
[InstanceEdit:4542306] Matthews, L, 2013-07-15
input[EntityWithAccessionedSequence:417169] ASF1A [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:2532790] HIRA [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:2532791] UBN1 [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:3878125] CABIN1 [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:3878156] Molecular dissection of formation of senescence-associated heterochromatin foci
[LiteratureReference:3878148] Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA
[LiteratureReference:3878157] Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells
[LiteratureReference:3878129] Human CABIN1 is a functional member of the human HIRA/UBN1/ASF1a histone H3.3 chaperone complex
[LiteratureReference:3878192] Definition of pRB- and p53-dependent and -independent steps in HIRA/ASF1a-mediated formation of senescence-associated heterochromatin foci
modified[InstanceEdit:3878137] Orlic-Milacic, M, 2013-07-12
[InstanceEdit:3878754] Orlic-Milacic, M, 2013-07-12
[InstanceEdit:4415004] Orlic-Milacic, M, 2013-08-23
[InstanceEdit:4416363] Orlic-Milacic, M, 2013-08-26
[InstanceEdit:4420304] Orlic-Milacic, M, 2013-09-03
[InstanceEdit:4420306] Orlic-Milacic, M, 2013-09-03
[InstanceEdit:4542310] Orlic-Milacic, M, 2013-09-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameInitiation of SAHF formation
output[Complex:3878132] HIRA:ASF1A:UBN1:CABIN1 [nucleoplasm] [Homo sapiens]
releaseDate2013-09-18
reviewed[InstanceEdit:4542303] Samarajiwa, Shamith, 2013-09-03
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:4545024] R-HSA-3878123.2
summation[Summation:3878753] The evolutionarily conserved complex of HIRA, ASF1A, UBN1 an...
(hasEvent)[Pathway:2559584] Formation of Senescence-Associated Heterochromatin Foci (SAHF) [Homo sapiens]
(precedingEvent)[Reaction:4647594] SAHF formation [Homo sapiens]
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No pathways have been reviewed or authored by Initiation of SAHF formation (3878123)
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