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Details on Person MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB

Class:IdReaction:3857329
_displayNameMAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB
_doReleaseTRUE
_timestamp2017-02-22 09:58:06
authored[InstanceEdit:3900006] Orlic-Milacic, M, 2013-07-15
catalystActivity[CatalystActivity:198713] protein serine/threonine kinase activity of p-T,Y MAPK dimers [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:3857307] Orlic-Milacic, M, 2013-07-09
edited[InstanceEdit:3901124] D'Eustachio, P, 2013-07-15
[InstanceEdit:4542306] Matthews, L, 2013-07-15
input[EntityWithAccessionedSequence:381378] CEBPB [nucleoplasm] [Homo sapiens]
[SimpleEntity:29358] ATP [nucleoplasm]
isChimericFALSE
literatureReference[LiteratureReference:3857341] Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6
modified[InstanceEdit:3858388] Orlic-Milacic, M, 2013-07-09
[InstanceEdit:3877064] Orlic-Milacic, M, 2013-07-10
[InstanceEdit:4415004] Orlic-Milacic, M, 2013-08-23
[InstanceEdit:4416363] Orlic-Milacic, M, 2013-08-26
[InstanceEdit:4420304] Orlic-Milacic, M, 2013-09-03
[InstanceEdit:4420306] Orlic-Milacic, M, 2013-09-03
[InstanceEdit:4542310] Orlic-Milacic, M, 2013-09-04
[InstanceEdit:6798229] Rothfels, Karen, 2015-09-17
[InstanceEdit:8979177] Orlic-Milacic, Marija, 2017-02-22
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameMAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB
output[EntityWithAccessionedSequence:3857343] p-T235-CEBPB [nucleoplasm] [Homo sapiens]
[SimpleEntity:113582] ADP [nucleoplasm]
precedingEvent
releaseDate2013-09-18
reviewed[InstanceEdit:4542303] Samarajiwa, Shamith, 2013-09-03
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:4545345] R-HSA-3857329.4
summation[Summation:3858369] Phosphorylation of CEBPB (C/EBP-beta) transcription factor o...
(hasEvent)[Pathway:2559582] Senescence-Associated Secretory Phenotype (SASP) [Homo sapiens]
(precedingEvent)[Reaction:3857328] RPS6KA1/2/3 phosphorylates CEBPB on S321 [Homo sapiens]
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