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Details on Person UniProt:Q6ZUV0 ACOT7L
| Class:Id | ReferenceGeneProduct:384515 |
|---|---|
| _chainChangeLog | chain:1-252 added on Fri February 6 2015 |
| _displayName | UniProt:Q6ZUV0 ACOT7L |
| _timestamp | 2025-02-21 19:56:47 |
| chain | chain:1-252 |
| checksum | E9C4DF4A82B87717 |
| comment | FUNCTION Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH.CATALYTIC ACTIVITY hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+)SUBUNIT Homodimer.SUBCELLULAR LOCATION Expressed in all tissues examined. Up-regulated in nasopharyngeal carcinoma (at protein level).DISEASE A functional variant in the transcriptional regulatory region of in ACOT7L cosegregates with disease phenotype in family affected by nasopharyngeal carcinoma. The variant creates an AP1-binding site that significantly enhances binding of AP1 to the promoter, resulting in up-regulation.CAUTION Could be the product of a pseudogene. The peptide used to produce antibodies against ACOT7L matches at 85% with ACOT7 and the antibodies may not be specific to ACOT7L. |
| created | [InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39 |
| description | recommendedName: Putative cytosolic acyl coenzyme A thioester hydrolase-like ecNumber: 3.1.2.2 alternativeName: Acyl-CoA thioesterase 7-like |
| geneName | ACOT7L BACHL |
| identifier | Q6ZUV0 |
| isSequenceChanged | FALSE |
| keyword | Cytoplasm Hydrolase Lipid metabolism Proteomics identification Reference proteome Repeat Serine esterase |
| modified | [InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18 [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 [InstanceEdit:423310] Kanapin, AA [InstanceEdit:435478] Kanapin, AA [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:4341137] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9767224] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | ACOT7L |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | BACHL_HUMAN |
| sequenceLength | 252 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:5690057] ACOT7L [cytosol] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q6ZUV0 ACOT7L (384515)
