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Details on Person Translocation of PDGF from ER to Golgi

Class:Id	Reaction:382053
_displayName	Translocation of PDGF from ER to Golgi
_doRelease	TRUE
_timestamp	2012-11-21 23:17:27
authored	[InstanceEdit:382627] Garapati, P V, Jassal, B, 2008-11-24 10:14:27
compartment	[Compartment:20699] Golgi membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:382060] Garapati, P V, 2008-11-21 20:21:25
edited	[InstanceEdit:382627] Garapati, P V, Jassal, B, 2008-11-24 10:14:27
input	[DefinedSet:381936] PDGF precursor dimers (AA, BB, A/B, CC, DD) [endoplasmic reticulum lumen] [Homo sapiens]
literatureReference	[LiteratureReference:380776] PDGF-AA and PDGF-BB biosynthesis: proprotein processing in the Golgi complex and lysosomal degradation of PDGF-BB retained intracellularly [LiteratureReference:380726] The PDGF family: four gene products form five dimeric isoforms
modified	[InstanceEdit:382623] Garapati, P V, 2008-11-24 00:33:18 [InstanceEdit:382631] Garapati, P V, 2008-11-24 10:24:46 [InstanceEdit:389087] Garapati, P V, 2008-12-19 10:29:26 [InstanceEdit:392248] Garapati, P V, 2009-03-01 16:05:31 [InstanceEdit:398091] Garapati, P V, 2009-03-16 16:42:15 [InstanceEdit:398095] Garapati, P V, 2009-03-16 16:59:41 [InstanceEdit:2648974] D'Eustachio, P, 2012-11-21 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Translocation of PDGF from ER to Golgi
output	[DefinedSet:381926] PDGF precursor dimers (AA, BB, A/B, CC, DD) [Golgi membrane] [Homo sapiens]
releaseDate	2009-04-01
reviewed	[InstanceEdit:382617] Heldin, CH, 2008-11-23 19:29:34
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:398480] R-HSA-382053.2
summation	[Summation:381891] All the newly synthesized PDGF chains are dimerized in the E...
(hasEvent)	[Pathway:186797] Signaling by PDGF [Homo sapiens]
(precedingEvent)	[Reaction:186785] PDGF-AA clevage by Furin [Homo sapiens] [BlackBoxEvent:382057] Release of novel PDGFs as latent factors [Homo sapiens] [Reaction:8865275] PDGF-BB clevage by Furin [Homo sapiens] [Reaction:8865276] PDGF-AB clevage by Furin [Homo sapiens]
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No pathways have been reviewed or authored by Translocation of PDGF from ER to Golgi (382053)