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Details on Person p130Cas and C3G bind PDGFR bound Crk

Class:Id	Reaction:382052
_displayName	p130Cas and C3G bind PDGFR bound Crk
_doRelease	TRUE
_timestamp	2022-02-04 22:02:30
authored	[InstanceEdit:382627] Garapati, P V, Jassal, B, 2008-11-24 10:14:27
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:382060] Garapati, P V, 2008-11-21 20:21:25
edited	[InstanceEdit:382627] Garapati, P V, Jassal, B, 2008-11-24 10:14:27
input	[Complex:381955] PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:201625] BCAR1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:913472] RAPGEF1 [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:381883] Identification of Tyr-762 in the platelet-derived growth factor alpha-receptor as the binding site for Crk proteins [LiteratureReference:380735] Signal transduction via platelet-derived growth factor receptors
modified	[InstanceEdit:382623] Garapati, P V, 2008-11-24 00:33:18 [InstanceEdit:382631] Garapati, P V, 2008-11-24 10:24:46 [InstanceEdit:389087] Garapati, P V, 2008-12-19 10:29:26 [InstanceEdit:392248] Garapati, P V, 2009-03-01 16:05:31 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:3008669] Jassal, B, 2013-02-01 [InstanceEdit:9763806] D'Eustachio, Peter, 2022-02-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	p130Cas and C3G bind PDGFR bound Crk
output	[Complex:381957] PDGF:Phospho-PDGF receptor dimer:Crk:p130Cas:C3G [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:382056] Crk binds to the active PDGF receptor [Homo sapiens] [Reaction:389083] Autophosphorylation of PDGF alpha receptors [Homo sapiens] [Reaction:389086] Autophosphorylation of PDGF alpha/beta receptors [Homo sapiens] [Reaction:186786] Autophosphorylation of PDGF beta receptors [Homo sapiens]
releaseDate	2009-04-01
reviewed	[InstanceEdit:382617] Heldin, CH, 2008-11-23 19:29:34
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:398380] R-HSA-382052.3
summation	[Summation:381886] The presence of both SH2 and SH3 domains in Crk proteins is ...
(hasEvent)	[Pathway:186763] Downstream signal transduction [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9775017] Update Tracker - [Reaction:382052] p130Cas and C3G bind PDGFR bound Crk - v80:[add_removeInput] [_UpdateTracker:9787705] Update Tracker - [Reaction:382052] p130Cas and C3G bind PDGFR bound Crk - v44:[add_removeInput]
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No pathways have been reviewed or authored by p130Cas and C3G bind PDGFR bound Crk (382052)