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Details on Person All the newly synthesized PDGF chains are dimerized in the E...

Class:IdSummation:381891
_displayNameAll the newly synthesized PDGF chains are dimerized in the E...
_timestamp2008-11-24 00:29:59
created[InstanceEdit:381880] Garapati, P V, 2008-11-21 17:56:41
literatureReference[LiteratureReference:380776] PDGF-AA and PDGF-BB biosynthesis: proprotein processing in the Golgi complex and lysosomal degradation of PDGF-BB retained intracellularly
[LiteratureReference:380726] The PDGF family: four gene products form five dimeric isoforms
modified[InstanceEdit:382619] Garapati, P V, 2008-11-24 00:29:42
textAll the newly synthesized PDGF chains are dimerized in the ER and thereafter transferred to the Golgi complex for proteolytic processing. The four PDGF chains assemble into disulphide-bonded dimers via homo- or heterodimerization, and five different dimeric isoforms have been described so far; PDGF-AA, PDGF-AB, PDGF-BB, PDGF-CC and PDGF-DD.
(summation)[Reaction:382053] Translocation of PDGF from ER to Golgi [Homo sapiens]
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No pathways have been reviewed or authored by All the newly synthesized PDGF chains are dimerized in the E... (381891)