Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person ER calcium channels open in response to activated PKA

Class:Id	BlackBoxEvent:381644
_displayName	ER calcium channels open in response to activated PKA
_doRelease	TRUE
_timestamp	2025-06-02 14:56:35
authored	[InstanceEdit:422341] May, B, 2009-05-28 03:44:04
catalystActivity	[CatalystActivity:9947020] potassium channel inhibitor activity of PKA catalytic subunit [cytosol]
catalystActivityReference	[CatalystActivityReference:9947016] potassium channel inhibitor activity of PKA catalytic subunit [cytosol] Glucagon-like peptide-1: regulation of insulin secretion and therapeutic potential
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:381677] May, B, 2008-11-19 21:15:12
edited	[InstanceEdit:422341] May, B, 2009-05-28 03:44:04
input	[DefinedSet:111877] Ca-channel (closed) [endoplasmic reticulum membrane] [Homo sapiens]
internalReviewed	[InstanceEdit:9947030] D'Eustachio, Peter, 2025-04-30
literatureReference	[LiteratureReference:448971] Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells [LiteratureReference:448972] Phosphorylation of inositol 1,4,5-trisphosphate receptors by cAMP-dependent protein kinase. Type I, II, and III receptors are differentially susceptible to phosphorylation and are phosphorylated in intact cells [LiteratureReference:446584] cAMP-dependent mobilization of intracellular Ca2+ stores by activation of ryanodine receptors in pancreatic beta-cells. A Ca2+ signaling system stimulated by the insulinotropic hormone glucagon-like peptide-1-(7-37) [LiteratureReference:381700] Mechanisms of action of glucagon-like peptide 1 in the pancreas [LiteratureReference:381661] The multiple actions of GLP-1 on the process of glucose-stimulated insulin secretion [LiteratureReference:381705] Molecular mechanism underlying glucagon-like peptide 1 induced calcium mobilization from internal stores in insulin-secreting beta TC3 cells [LiteratureReference:381641] Glucagon-like peptide-1: regulation of insulin secretion and therapeutic potential
modified	[InstanceEdit:383210] Gopinathrao, G, 2008-11-24 14:43:07 [InstanceEdit:422154] D'Eustachio, P, 2009-05-26 22:22:55 [InstanceEdit:422556] D'Eustachio, P, 2009-06-02 01:00:41 [InstanceEdit:425249] May, B, 2009-06-03 [InstanceEdit:446582] May, B, 2009-11-13 [InstanceEdit:448968] May, B, 2009-11-27 [InstanceEdit:5252146] May, B, 2014-02-05 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9947017] D'Eustachio, Peter, 2025-04-30 [InstanceEdit:9947029] D'Eustachio, Peter, 2025-04-30 [InstanceEdit:9953426] D'Eustachio, Peter, 2025-06-02
name	ER calcium channels open in response to activated PKA
output	[DefinedSet:111873] Ca-channel (open) [endoplasmic reticulum membrane] [Homo sapiens]
precedingEvent	[Reaction:381707] PKA:AKAP79:IQGAP1 complex dissociates to active PKA subunits in response to cAMP [Homo sapiens] [Reaction:381607] Activated Adenylyl cyclase synthesizes cyclic AMP [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2009-06-24
reviewed	[InstanceEdit:422557] Gillespie, ME, 2009-06-02 00:59:01 [InstanceEdit:9953425] Hill, David P, 2025-06-02
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104570] R-HSA-381644.5
structureModified	[InstanceEdit:9947017] D'Eustachio, Peter, 2025-04-30
summation	[Summation:381696] Activated Protein Kinase A promotes the release of calcium f...
(hasEvent)	[Pathway:381676] Glucagon-like Peptide-1 (GLP1) regulates insulin secretion [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:265166] Exocytosis of Insulin [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9791355] Update Tracker - [BlackBoxEvent:381644] ER calcium channels open in response to activated PKA - v31:[addLiteratureReference] [_UpdateTracker:9953696] Update Tracker - [BlackBoxEvent:381644] ER calcium channels open in response to activated PKA - v93:[addRegulator, removeCatalystActivity]
[Change default viewing format]

No pathways have been reviewed or authored by ER calcium channels open in response to activated PKA (381644)