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Details on Person Glucagon-like peptide-1: regulation of insulin secretion and therapeutic potential

Class:IdLiteratureReference:381641
_displayNameGlucagon-like peptide-1: regulation of insulin secretion and therapeutic potential
_timestamp2008-11-19 21:14:18
author[Person:381614] Gromada, J
[Person:381723] Brock, B
[Person:381597] Schmitz, O
[Person:264316] Rorsman, P
created[InstanceEdit:381677] May, B, 2008-11-19 21:15:12
journalBasic Clin Pharmacol Toxicol
pages252-62
pubMedIdentifier15569269
titleGlucagon-like peptide-1: regulation of insulin secretion and therapeutic potential
volume95
year2004
(literatureReference)[Reaction:381607] Activated Adenylyl cyclase synthesizes cyclic AMP [Homo sapiens]
[Reaction:381608] cAMP activates EPAC2 [Homo sapiens]
[Reaction:381612] GLP1R binds GLP1 [Homo sapiens]
[BlackBoxEvent:381644] ER calcium channels open in response to activated PKA [Homo sapiens]
[Reaction:381668] cAMP activates EPAC1 [Homo sapiens]
[Pathway:381676] Glucagon-like Peptide-1 (GLP1) regulates insulin secretion [Homo sapiens]
[Reaction:381704] G(s):GTP activates Adenylyl cyclase [Homo sapiens]
[Reaction:381706] GLP1R:GLP1 activates G(s) [Homo sapiens]
[Reaction:381707] PKA:AKAP79:IQGAP1 complex dissociates to active PKA subunits in response to cAMP [Homo sapiens]
[BlackBoxEvent:381713] Potassium voltage-gated channels close in reponse to PKA [Homo sapiens]
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