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Details on Person G-protein-coupled receptors and islet function-implications for treatment of type 2 diabetes

Class:Id	LiteratureReference:381633
_displayName	G-protein-coupled receptors and islet function-implications for treatment of type 2 diabetes
_timestamp	2008-11-19 21:14:17
author	[Person:381654] Winzell, MS [Person:381632] Ahren, B
created	[InstanceEdit:381677] May, B, 2008-11-19 21:15:12
journal	Pharmacol Ther
pages	437-48
pubMedIdentifier	17900700
title	G-protein-coupled receptors and islet function-implications for treatment of type 2 diabetes
volume	116
year	2007
(literatureReference)	[RegulationReference:9642641] Negative regulation by 'Voltage-gated Calcium Channels Type Cav1 (closed) [plasma membrane]' Both G i and G o heterotrimeric G proteins are required to exert the full effect of norepinephrine on the beta-cell K ATP channel [RegulationReference:9642657] Negative regulation by 'G-alpha(i,o):GTP [plasma membrane]' Both G i and G o heterotrimeric G proteins are required to exert the full effect of norepinephrine on the beta-cell K ATP channel [RegulationReference:9643006] Negative regulation by 'Potassium Channel, open (pancreatic beta cell) [plasma membrane]' Both G i and G o heterotrimeric G proteins are required to exert the full effect of norepinephrine on the beta-cell K ATP channel [Summation:399973] Studies using inhibitors and pancreatic beta cells have esta... [BlackBoxEvent:265166] Exocytosis of Insulin [Homo sapiens] [Pathway:381676] Glucagon-like Peptide-1 (GLP1) regulates insulin secretion [Homo sapiens] [Reaction:381704] G(s):GTP activates Adenylyl cyclase [Homo sapiens] [Reaction:381706] GLP1R:GLP1 activates G(s) [Homo sapiens] [Reaction:399995] Muscarinic Acetylcholine Receptor M3 activates Gq [Homo sapiens] [Reaction:400012] Acetylcholine binds Muscarinic Acetylcholine Receptor M3 [Homo sapiens] List all 19 refering instances
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