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Details on Person IGF1,2 [extracellular region]
| Class:Id | DefinedSet:381451 |
| _displayName | IGF1,2 [extracellular region] |
| _timestamp | 2014-02-05 20:29:04 |
| compartment | [Compartment:984] extracellular region |
| created | [InstanceEdit:381505] May, B, 2008-11-19 20:29:10 |
| hasMember |
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| modified | [InstanceEdit:2404181] May, B, 2012-07-16 [InstanceEdit:5252148] May, B, 2014-02-05 |
| name | IGF1,2 Insulin-like Growth Factor |
| species | [Species:48887] Homo sapiens |
| stableIdentifier | [StableIdentifier:398985] R-HSA-381451.1 |
| (hasComponent) | [Complex:381423] IGF:IGFBP5:ALS [extracellular region] [Homo sapiens] [Complex:381473] IGF:IGFBP2 [extracellular region] [Homo sapiens] [Complex:381482] IGF:IGFBP6 [extracellular region] [Homo sapiens] [Complex:381509] IGF:IGFBP4 [extracellular region] [Homo sapiens] [Complex:381536] IGF:IGFBP3:ALS [extracellular region] [Homo sapiens] [Complex:381539] IGF:IGFBP1 [extracellular region] [Homo sapiens] [Complex:2404186] IGF1,2:IGF1R [plasma membrane] [Homo sapiens] [Complex:2404189] IGF1,2:p-3Y-IGF1R [plasma membrane] [Homo sapiens] |
| (hasMember) | [DefinedSet:481033] Platelet alpha granule contents [extracellular region] [Homo sapiens] |
| (input) | [Reaction:381412] IGFBP2 binds IGF forming IGF:IGFBP2 [Homo sapiens] [Reaction:381487] IGFBP1 binds IGF forming IGF:IGFBP1 [Homo sapiens] [Reaction:381496] Formation of the IGF:IGFBP3:ALS complex [Homo sapiens] [Reaction:381503] IGFBP6 binds IGF forming IGF:IGFBP6 [Homo sapiens] [Reaction:381543] IGFBP4 binds IGF forming IGF:IGFBP4 [Homo sapiens] [Reaction:381545] Formation of the IGF:IGFBP5:ALS complex [Homo sapiens] [Reaction:2404200] IGF1,2 binds IGF1R [Homo sapiens] |
| (output) | [Reaction:381435] Matrix metalloproteinase proteolyzes IGF:IGFBP3:ALS [Homo sapiens] [Reaction:381446] Thrombin proteolyzes IGF:IGFBP3:ALS [Homo sapiens] [Reaction:381461] Plasmin proteolyzes IGF:IGFBP-3:ALS [Homo sapiens] [Reaction:381466] Prostate-specific Antigen proteolyzes IGF:IGFBP3:ALS [Homo sapiens] [Reaction:381500] Cathepsin G proteolyzes IGF:IGFBP3:ALS [Homo sapiens] [Reaction:381518] PAAP-A proteolyzes IGF:IGFBP4 [Homo sapiens] [Reaction:381537] PAPP-A2 proteolyzes IGF:IGFBP5:ALS [Homo sapiens] |
| (replacementInstances) | [_Deleted:9774065] Deletion of instance: 3006323 |
| (updatedInstance) | [_UpdateTracker:9869804] Update Tracker - [DefinedSet:381451] IGF1,2 [extracellular region] - v34:[updateContainedMemberOrCandidate] [_UpdateTracker:9872880] Update Tracker - [DefinedSet:381451] IGF1,2 [extracellular region] - v42:[add_removeHasMember, modifyName] [_UpdateTracker:9889107] Update Tracker - [DefinedSet:381451] IGF1,2 [extracellular region] - v48:[modifyName] |
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No pathways have been reviewed or authored by IGF1,2 [extracellular region] (381451)