Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person IGF1,2 [extracellular region]

Class:IdDefinedSet:381451
_displayNameIGF1,2 [extracellular region]
_timestamp2014-02-05 20:29:04
compartment[Compartment:984] extracellular region
created[InstanceEdit:381505] May, B, 2008-11-19 20:29:10
hasMember
modified[InstanceEdit:2404181] May, B, 2012-07-16
[InstanceEdit:5252148] May, B, 2014-02-05
nameIGF1,2
Insulin-like Growth Factor
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:398985] R-HSA-381451.1
(hasComponent)[Complex:381423] IGF:IGFBP5:ALS [extracellular region] [Homo sapiens]
[Complex:381473] IGF:IGFBP2 [extracellular region] [Homo sapiens]
[Complex:381482] IGF:IGFBP6 [extracellular region] [Homo sapiens]
[Complex:381509] IGF:IGFBP4 [extracellular region] [Homo sapiens]
[Complex:381536] IGF:IGFBP3:ALS [extracellular region] [Homo sapiens]
[Complex:381539] IGF:IGFBP1 [extracellular region] [Homo sapiens]
[Complex:2404186] IGF1,2:IGF1R [plasma membrane] [Homo sapiens]
[Complex:2404189] IGF1,2:p-3Y-IGF1R [plasma membrane] [Homo sapiens]
(hasMember)[DefinedSet:481033] Platelet alpha granule contents [extracellular region] [Homo sapiens]
(input)[Reaction:381412] IGFBP2 binds IGF forming IGF:IGFBP2 [Homo sapiens]
[Reaction:381487] IGFBP1 binds IGF forming IGF:IGFBP1 [Homo sapiens]
[Reaction:381496] Formation of the IGF:IGFBP3:ALS complex [Homo sapiens]
[Reaction:381503] IGFBP6 binds IGF forming IGF:IGFBP6 [Homo sapiens]
[Reaction:381543] IGFBP4 binds IGF forming IGF:IGFBP4 [Homo sapiens]
[Reaction:381545] Formation of the IGF:IGFBP5:ALS complex [Homo sapiens]
[Reaction:2404200] IGF1,2 binds IGF1R [Homo sapiens]
(output)[Reaction:381435] Matrix metalloproteinase proteolyzes IGF:IGFBP3:ALS [Homo sapiens]
[Reaction:381446] Thrombin proteolyzes IGF:IGFBP3:ALS [Homo sapiens]
[Reaction:381461] Plasmin proteolyzes IGF:IGFBP-3:ALS [Homo sapiens]
[Reaction:381466] Prostate-specific Antigen proteolyzes IGF:IGFBP3:ALS [Homo sapiens]
[Reaction:381500] Cathepsin G proteolyzes IGF:IGFBP3:ALS [Homo sapiens]
[Reaction:381518] PAAP-A proteolyzes IGF:IGFBP4 [Homo sapiens]
[Reaction:381537] PAPP-A2 proteolyzes IGF:IGFBP5:ALS [Homo sapiens]
(replacementInstances)[_Deleted:9774065] Deletion of instance: 3006323
(updatedInstance)[_UpdateTracker:9869804] Update Tracker - [DefinedSet:381451] IGF1,2 [extracellular region] - v34:[updateContainedMemberOrCandidate]
[_UpdateTracker:9872880] Update Tracker - [DefinedSet:381451] IGF1,2 [extracellular region] - v42:[add_removeHasMember, modifyName]
[_UpdateTracker:9889107] Update Tracker - [DefinedSet:381451] IGF1,2 [extracellular region] - v48:[modifyName]
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No pathways have been reviewed or authored by IGF1,2 [extracellular region] (381451)