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Details on Person ATF4 [nucleoplasm]
Class:Id EntityWithAccessionedSequence:381016
_displayName ATF4 [nucleoplasm]
_timestamp 2010-12-02 14:43:46
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:381159] May, B, 2008-11-19 16:17:44
endCoordinate 351
modified [InstanceEdit:3132750] Wu, G, 2013-02-13
name ATF4
referenceEntity [ReferenceGeneProduct:50471] UniProt:P18848 ATF4 [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:1106293] R-HSA-381016.1
startCoordinate 1
(activeUnit) [PositiveGeneExpressionRegulation:9761851] Positive gene expression regulation by 'SLC7A11 gene:p-AcK-NFE2L2:ATF4 [nucleoplasm]'
(hasComponent) [Complex:9635818] ATF4 dimer [nucleoplasm] [Homo sapiens] [Complex:9635875] ATF4:CEBPB gene [nucleoplasm] [Homo sapiens] [Complex:9635905] ATF4:ATF3 gene [nucleoplasm] [Homo sapiens] [Complex:9644309] ATF4:CEBPB,CEBPG [nucleoplasm] [Homo sapiens] [Complex:9653892] ATF3:ATF4:CEBPB:CHAC1 gene [nucleoplasm] [Homo sapiens] [Complex:9654219] ATF4:CEBPB,CEBPG,DDIT3 [nucleoplasm] [Homo sapiens] [Complex:9654773] ATF4:PPP1R15A gene [nucleoplasm] [Homo sapiens] [Complex:9655080] ATF4:DDIT3 gene [nucleoplasm] [Homo sapiens] [Complex:9761741] SLC7A11 gene:p-AcK-NFE2L2:ATF4 [nucleoplasm] [Homo sapiens]
(input) [Reaction:9635804] ATF4 and phospho-ATF2 bind the DDIT3 promoter [Homo sapiens] [Reaction:9635892] ATF4 binds the ATF3 gene [Homo sapiens] [Reaction:9635915] ATF4 and CEBPB,CEBPG bind the ASNS gene [Homo sapiens] [Reaction:9635927] ATF4 and a CEBP protein bind the TRIB3 promoter [Homo sapiens] [Reaction:9635936] ATF4 binds the CEBPB gene [Homo sapiens] [Reaction:9653742] ATF4 and a CEBP protein bind the ATF5 promoter [Homo sapiens] [Reaction:9653893] ATF4, CEBPB, and ATF3 bind the CHAC1 promoter [Homo sapiens] [Reaction:9654752] ATF4 binds the PPP1R15A (GADD34) promoter [Homo sapiens] [Reaction:9655086] ATF4 binds the DDIT3 promoter [Homo sapiens] [Reaction:9761815] AcK-NFE2L2 and ATF4 bind the SLC7A11 gene [Homo sapiens]
(output) [BlackBoxEvent:381128] Translation of ATF4 [Homo sapiens]
(physicalEntity) [CatalystActivity:381097] unknown activity of ATF4 [nucleoplasm]
(regulator) [PositiveGeneExpressionRegulation:1791199] Positive gene expression regulation by 'ATF4 [nucleoplasm]' [PositiveGeneExpressionRegulation:1791200] Positive gene expression regulation by 'ATF4 [nucleoplasm]' [PositiveGeneExpressionRegulation:1791203] Positive gene expression regulation by 'ATF4 [nucleoplasm]' [PositiveGeneExpressionRegulation:1791222] Positive gene expression regulation by 'ATF4 [nucleoplasm]' [PositiveGeneExpressionRegulation:1791227] Positive gene expression regulation by 'ATF4 [nucleoplasm]' [PositiveGeneExpressionRegulation:1791243] Positive gene expression regulation by 'ATF4 [nucleoplasm]'
(updatedInstance) [_UpdateTracker:9874798] Update Tracker - [EntityWithAccessionedSequence:381016] ATF4 [nucleoplasm] - v44:[modifyEndCoordinate]
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Pathways
No pathways have been reviewed or authored by ATF4 [nucleoplasm] (381016)